Tag: M.W=150-200

In 2021.0 J MOL STRUCT published article about MULTICOMPONENT REACTION; ANTIBACTERIAL ACTIVITY; DERIVATIVES; INHIBITORS; ANTIFUNGAL; DISCOVERY in [Jilloju, Shankara Chary; Jatavath, Mohanbabu; Rao, Mesineni Anand] Osmania Univ, Dept Chem, Hyderabad 500007, Telangana, India; [Jilloju, Shankara Chary] Mahatma Gandhi Univ, Dept Chem & Pharmaceut Sci, Nalgonda 508254, Telangana, India; [Jilloju, Parameshwara Chary] Natl Inst Technol, Dept Chem, Warangal 506004, Telangana, India in 2021.0, Cited 50.0. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6. Safety of 3-Nitrobenzaldehyde

A series of 3-(2-benzylidenehydrazinyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines were synthesized via a one-pot, three-component protocol. The new derivatives were purified and confirmed by their spectroscopic (FT-IR, H-1 NMR, C-13 NMR and Mass) and elemental analysis. Further, the synthesized compounds were screened for the binding interactions with p38MAPK (PDB id: 3BX5) by in-silico molecular docking studies. amongst the synthesized compounds 4f, 4 g, and 4k were interacted with good dock score at active site of p38MAP Kinase. (C) 2021 Elsevier B.V. All rights reserved.

Safety of 3-Nitrobenzaldehyde. About 3-Nitrobenzaldehyde, If you have any questions, you can contact Jilloju, SC; Jilloju, PC; Jatavath, M; Rao, MA or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Name: Benzophenone. Authors Guo, WX; Zhao, L; Cui, NB; Gong, X; Huang, Y; Li, ZL; Lin, B; Zhou, X; Yang, P in ELSEVIER published article about in [Guo, Wanxin; Zhao, Lei; Cui, Naibin; Gong, Xue; Huang, Yu; Li, Zhenli; Zhou, Xue; Yang, Peng] Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Peoples R China; [Lin, Bin] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China in 2021.0, Cited 28.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

Visual detection of p-toluenesulfonic acid (pTSA) is very important due to its health-harmful effects, but remains less investigated. In this study, a TGM (Triethylene Glycol Monomethyl ether) derived calix [4] carbazole was found to be able to selectively encapsulate pTSA by its cone conformation, thus specifically detecting it visually. To the best of our knowledge, it is the first case of pTSA visual detection based on host-guest binding triggered charge transfer. ? 2021 Elsevier B.V. All rights reserved.

Welcome to talk about 119-61-9, If you have any questions, you can contact Guo, WX; Zhao, L; Cui, NB; Gong, X; Huang, Y; Li, ZL; Lin, B; Zhou, X; Yang, P or send Email.. Name: Benzophenone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

SDS of cas: 99-61-6. Authors Babaee, S; Chehardoli, G; Akbarzadeh, T; Zolfigol, MA; Mahdavi, M; Rastegari, A; Moghadam, FH; Najafi, Z in WILEY-V C H VERLAG GMBH published article about in [Babaee, Saeed; Zolfigol, Mohammad Ali] Bu Ali Sina Univ, Fac Chem, Dept Organ Chem, Hamadan 6517838683, Hamadan, Iran; [Chehardoli, Gholamabbas; Najafi, Zahra] Hamadan Univ Med Sci, Sch Pharm, Dept Med Chem, Hamadan 6517838678, Iran; [Akbarzadeh, Tahmineh; Rastegari, Arezoo] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran 1417614411, Iran; [Mahdavi, Mohammad] ACECR, Royan Inst Biotechnol, Cell Sci Res Ctr, Dept Cellular Biotechnol, Esfahan 8165131378, Iran; [Homayouni Moghadam, Farshad] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran 1411713137, Iran in 2021.0, Cited 32.0. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6

A novel series of tacrine based cyclopentapyranopyridine- and tetrahydropyranoquinoline-kojic acid derivatives were designed, synthesized, and evaluated as anti-cholinesterase agents. The chemical structures of all target compounds were characterized by H-1-NMR, C-13-NMR, and elemental analyses. The synthesized compounds mostly inhibited acetylcholinesterase enzyme (AChE) with IC50 values of 4.18-48.71 mu M rather than butyrylcholinesterase enzyme (BChE) with IC50 values of >100 mu M. Among them, cyclopentapyranopyridine-kojic acid derivatives showed slightly better AChE inhibitory activity compared to tetrahydropyranoquinoline-kojic acid. The compound 10-amino-2-(hydroxymethyl)-11-(4-isopropylphenyl)-7,8,9,11-tetrahydro-4H-cyclopenta[b]pyrano[2 ‘,3 ‘ : 5,6]pyrano[3,2-e]pyridin-4-one (6f) bearing 4-isopropylphenyl moiety and cyclopentane ring exhibited the highest anti-AChE activity with IC50 value of 4.18 mu M. The kinetic study indicated that the compound 6f acts as a mixed inhibitor and the molecular docking studies also illustrated that the compound 6f binds to both the catalytic site (CS) and peripheral anionic site (PAS) of AChE. The compound 6f showed moderate neuroprotective properties against H2O2-induced cytotoxicity in PC12 cells. The theoretical ADME study also predicted good drug-likeness for the compound 6f. Based on these results, the compound 6f seems to be a very promising AChE inhibitor for the treatment of Alzheimer’s disease.

SDS of cas: 99-61-6. Bye, fridends, I hope you can learn more about C7H5NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Copper incorporated hydroxyapatite encapsulated Kit-6 mesoporous silica as a novel and recoverable nanocatalyst for the synthesis of quinazolines WOS:000658583100001 published article about HYBRID MAGNETIC NANOCATALYST; EFFICIENT SYNTHESIS; CATALYST; DERIVATIVES; OXIDATION; CRYSTALLIZATION; GROWTH; OXIDES; MILD in [Pirdelzendeh, Dornaz] Univ Guilan, Dept Chem, Univ Campus 2, Rasht, Iran; [Mamaghani, Manouchehr; Shirini, Farhad; Sheykhan, Mehdi] Univ Guilan, Fac Sci, Dept Chem, POB 41335-1914, Rasht, Iran in 2021.0, Cited 60.0. Formula: C7H5NO3. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6

This research work describes the synthesis of copper incorporated hydroxyapatite encapsulated Kit-6 (Cu@HAp@KIT-6) as a novel and impactful nanocatalyst and evaluation of its activity in the synthesis of quinazoline derivatives by a three-component reaction of 2-amino-5-chlorobenzophenone, ammonium acetate, and aromatic aldehydes in ethanol. This practical method produced the products with high to excellent yields (85-96%) and reasonable reaction time (1 h). The nanocatalyst was characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscope, energy dispersive analysis of X-rays, thermogravimetric analysis, differential thermogravimetric, and Transmission electron microscopy. The recyclability of the catalyst was also examined which preserved its main catalytic activity after six consecutive runs.

Bye, fridends, I hope you can learn more about C7H5NO3, If you have any questions, you can browse other blog as well. See you lster.. Formula: C7H5NO3

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Category: thiomorpholine. Authors Guo, WX; Zhao, L; Cui, NB; Gong, X; Huang, Y; Li, ZL; Lin, B; Zhou, X; Yang, P in ELSEVIER published article about in [Guo, Wanxin; Zhao, Lei; Cui, Naibin; Gong, Xue; Huang, Yu; Li, Zhenli; Zhou, Xue; Yang, Peng] Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Peoples R China; [Lin, Bin] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China in 2021.0, Cited 28.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

Visual detection of p-toluenesulfonic acid (pTSA) is very important due to its health-harmful effects, but remains less investigated. In this study, a TGM (Triethylene Glycol Monomethyl ether) derived calix [4] carbazole was found to be able to selectively encapsulate pTSA by its cone conformation, thus specifically detecting it visually. To the best of our knowledge, it is the first case of pTSA visual detection based on host-guest binding triggered charge transfer. ? 2021 Elsevier B.V. All rights reserved.

Welcome to talk about 119-61-9, If you have any questions, you can contact Guo, WX; Zhao, L; Cui, NB; Gong, X; Huang, Y; Li, ZL; Lin, B; Zhou, X; Yang, P or send Email.. Category: thiomorpholine

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article New soluble, transparent and heat-resistant poly(ether amide)s based on 10,10-bis[4-(4-aminophenoxy)-3-methylphenyl]-9(10H)-anthrone WOS:000546648300001 published article about HIGH OPTICAL TRANSPARENCY; AROMATIC POLYAMIDES; ORGANOSOLUBLE POLYAMIDES; LIGHT COLOR; UNITS; LINKAGES in [Li, Juan; Zhong, Ming; Sang, Xiao-Yan; Huang, Zhen-Zhong] Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China in 2021, Cited 24. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8. Application In Synthesis of Anthrone

10,10-Bis[4-(4-aminophenoxy)-3-methylphenyl]-9(10H)-anthrone, as a new aromatic diamine, was synthesized from 9(10H)-anthrone by three-step procedure. Low-temperature polycondensation of this diamine with various aromatic dicarboxylic acid dichlorides produced a series of new cardo poly(ether amide)s with moderate to high inherent viscosities of 0.86-1.43 dL g(-1)while the weight-average and number-average molecular weights were in the range of 48,600-59,800 and 29,800-35,600 g mol(-1), respectively. All the polymers were readily soluble in polar solvents such asN,N-dimethylacetamide (DMAc),N,N-dimethylformamide,N-methyl-2-pyrrolidinone, dimethyl sulfoxide, and pyridine, and afforded transparent, flexible, and strong films upon casting from DMAc solvent. These polymers had glass transition temperatures of 254-297 degrees C, 10% weight loss temperatures of 493-505 degrees C, and char yields of 61-64% at 800 degrees C in nitrogen. All polymers were amorphous and their films exhibited tensile strength of 80.7-101.4 MPa, elongation at break of 8.0-12.8%, and tensile modulus of 1.9-2.6 GPa. These polymers had low moisture uptake in the range of 2.13-4.02% and high transparency with an ultraviolet-visible absorption cutoff wavelength in the 322-375 nm range.

Application In Synthesis of Anthrone. Bye, fridends, I hope you can learn more about C14H10O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

HPLC of Formula: C13H10O. In 2021.0 CHEM RES TOXICOL published article about PERSONAL CARE PRODUCTS; UV-FILTER OCTOCRYLENE; ESTROGENIC POTENCY; METABOLITES; INGREDIENTS; DERIVATIVES; SAFETY in [Downs, C. A.; Stien, Didier; Rodrigues, Alice M. S.; Lebaron, Philippe] Sorbonne Univ, CNRS, Lab Biodiversite & Biotechnol Microbiennes, USR3579,Observ Oceanol, F-66650 Banyuls Sur Mer, France; [Downs, C. A.] Haereticus Environm Lab, Clifford, VA 24533 USA in 2021.0, Cited 65.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9.

Benzophenone is a mutagen, carcinogen, and endocrine disruptor. Its presence in food products or food packaging is banned in the United States. Under California Proposition 65, there is no safe harbor for benzophenone in any personal care products, including sunscreens, anti-aging creams, and moisturizers. The purpose of this study was to determine (1) if benzophenone was present in a wide variety of commercial sun protection factor (SPF)/sunscreen products, (2) whether benzophenone concentration in the product increased over time, and (3) if the degradation of octocrylene was the likely source for benzophenone contamination. Benzophenone concentration was assayed in nine commercial sunscreen products from the European Union and eight from the United States (in triplicate), including two single ingredient sources of octocrylene. These same SPF items were subjected to the United States Food and Drug Administration (U.S. FDA)-accelerated stability aging protocol for 6 weeks. Benzophenone was measured in the accelerated-aged products. Sixteen octocrylene-containing product lines that were recently purchased had an average concentration of 39 mg/kg benzophenone, ranging from 6 mg/kg to 186 mg/kg. Benzophenone was not detectable in the product that did not contain octocrylene. After subjecting the 17 products to the U.S. FDA-accelerated stability method, the 16 octocrylene-containing products had an average concentration of 75 mg/kg, ranging from 9.8 mg/kg to 435 mg/kg. Benzophenone was not detectable in the product that did not contain octocrylene. Benzophenone was detected in the pure octocrylene manufactured ingredient. Octocrylene generates benzophenone through a retro-aldol condensation. In vivo, up to 70% of the benzophenone in these sunscreen products may be absorbed through the skin. U.S. FDA has established a zero tolerance for benzophenone as a food additive. In the United States, there were 2999 SPF products containing octocrylene in 2019. The safety of octocrylene as a benzophenone generator in SPF or any consumer products should be expeditiously reviewed by regulatory agencies.

HPLC of Formula: C13H10O. Welcome to talk about 119-61-9, If you have any questions, you can contact Downs, CA; DiNardo, JC; Stien, D; Rodrigues, AMS; Lebaron, P or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2021.0 ORGANOMETALLICS published article about HOMOLEPTIC LANTHANIDE COMPLEXES; STRUCTURAL-CHARACTERIZATION; METAL COMPLEXES; PRECURSORS; REACTIVITY; CHEMISTRY; CATALYSTS; CRYSTAL; AMIDES; SCANDIUM(III) in [Boteju, Kasuni C.; Venkatesh, Amrit; Wan, Suchen; Rossini, Aaron J.; Sadow, Aaron D.] Iowa State Univ, US DOE, Ames Lab, Ames, IA 50011 USA; [Boteju, Kasuni C.; Venkatesh, Amrit; Chu, Yang-Yun; Ellern, Arkady; Rossini, Aaron J.; Sadow, Aaron D.] Iowa State Univ, Dept Chem, Ames, IA 50011 USA in 2021.0, Cited 54.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9. HPLC of Formula: C13H10O

Three new hydridosilazido ligands, -N(SiHMe2)Aryl (Aryl = Ph, 2,6-C6Me2H3 (dmp), 2,6-C(6)iPr(2)H(3) (dipp)) and their rare-earth complexes Ln{N(SiHMe2)Aryl}(3)(THF)(n) (Ln = Sc, Y, Lu; Aryl = Ph, n = 2; Aryl = dmp, n = 1; Aryl = dipp, n = 0) were synthesized to study the relationships among ligand steric properties, secondary Ln <- H-Si bonding, and the reactivity of amide and SiH groups. In these compounds, the steric encumbrance of the aryl group was systematically increased from phenyl to 2,6-dimethylphenyl to 2,6-diisopropylphenyl. NMR, IR, and X-ray diffraction studies of the complexes characterize the number of secondary interactions and additional THF ligands coordinated to the rare-earth centers. The complexes with the smallest phenylsilazido ligands, Ln{N(SiHMe2)PH}(3)(THF)(2), contain features associated with three nonbridging 2-center-2-electron (2c-2e) Si-H bonds. Characterization of intermediate-sized Ln{N(SiHMe2)dmp}(3)THF reveals three and two Li <- H-Si interactions for yttrium and lutetium analogues, respectively, with both metals having one coordinated THF per complex Ln{N(SiHMe2)dipp}(3) is formed solvent-free, and all three ligands adopt Li <- H-Si bonding modes. The reaction between Ln{N(SiHMe2)dipp}(3) and ketones provides the hydrosilylated product via addition of C=O and Si-H bonds, which occurs rapidly even at low temperature. This reaction is proposed to occur through an associative mechanism on the basis of negative activation entropy measured for substitution of pyridine in Ln{N(SiHMe2)dipp}(3)center dot NC5H5. Bye, fridends, I hope you can learn more about C13H10O, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C13H10O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Parthasarathy, M; Adigopula, S; Gownivari, H; Mudhivedu, G; Vasudevan, A; Ulaganadhan, DS in [Parthasarathy, Meera] Sree Vidyanikethan Engn Coll, Dept Basic Sci & Humanities, Tirupati 517102, Andhra Pradesh, India; [Adigopula, Srikanth; Gownivari, Harichandana; Mudhivedu, Gnanaprasanna; Vasudevan, Anitha; Ulaganadhan, Dhinakaran Sorakka] Sree Vidyanikethan Degree Coll, Dept Chem Sci, Tirupati 517102, Andhra Pradesh, India published Carbon-Coated Magnetic Iron Oxide Nanoparticles as Green Catalysts for Aromatic Nitration in 2021.0, Cited 26.0. COA of Formula: C7H5NO3. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6.

Nitration of aromatic compounds is an important industrial process, which creates significant environmental pollution because of the harsh mineral acid catalysts. In this work, we report the synthesis and application of magnetic iron oxide nanoparticles as green catalysts for aromatic nitration. Magnetic iron oxide nanoparticles were synthesized by co-precipitation method and tested for nitration reactions on selected aromatic substrates, phenol, benzaldehyde, methylbenzoate, o-cresol and p-cresol. For the nitration reactions, sodium nitrite was used as the nitro-source and hydrogen peroxide as the oxidant. Effect of reaction conditions like, solvent, temperature and microwave treatment were studied. The magnetic nanoparticles were found to be more stable after coating with a carbon shell by a one-pot carbonization method. The reactions were fast with good product yield under solvent-free microwave conditions. The nano-catalyst was recovered magnetically after the reaction and reused for three batches of nitration, without significant loss in catalytic activity. The nanoparticles were characterized using scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), X-ray diffractometry (XRD) and FTIR spectroscopy.

COA of Formula: C7H5NO3. Welcome to talk about 99-61-6, If you have any questions, you can contact Parthasarathy, M; Adigopula, S; Gownivari, H; Mudhivedu, G; Vasudevan, A; Ulaganadhan, DS or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Sorrentino, JP; Orsi, DL; Altman, RA in AMER CHEMICAL SOC published article about in [Sorrentino, Jacob P.] Univ Kansas, Dept Med Chem, Lawrence, KS 66045 USA; [Orsi, Douglas L.] Broad Inst Harvard & MIT, Cambridge, MA 02142 USA; [Altman, Ryan A.] Purdue Univ, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47906 USA; [Altman, Ryan A.] Purdue Univ, Dept Chem, W Lafayette, IN 47906 USA in 2021.0, Cited 35.0. Product Details of 99-61-6. The Name is 3-Nitrobenzaldehyde. Through research, I have a further understanding and discovery of 99-61-6

The substitution of hydrogen atoms with fluorine in bioactive molecules can greatly impact physicochemical, pharmacokinetic, and pharmacodynamic properties. However, current synthetic methods cannot readily access many fluorinated motifs, which impedes utilization of these groups. Thus, the development of new methods to introduce fluorinated functional groups is critical for developing the next generation of biological probes and therapeutic agents. The synthesis of one such substructure, the alpha,alpha-difluoroalkylthioether, typically requires specialized conditions that necessitate early-stage installation. A late-stage and convergent approach to access alpha,alpha-difluoroalkylthioethers could involve nucleophilic addition of thiols across gem-difluorostyrenes. Unfortunately, under basic conditions, nucleophilic addition to gem-difluorostyrenes generates an anionic intermediate that can undergo facile elimination of fluoride to generate alpha-fluorovinylthioethers. To overcome this decomposition, we herein exploit an acid-based catalyst system to facilitate simultaneous nucleophilic addition and protonation of the unstable intermediate. Ultimately, the optimized mild conditions afford the desired alpha,alpha-difluoroalkylthioethers in high selectivity and moderate to excellent yields. These alpha,alpha-difluoroalkylthioethers are less nucleophilic and more oxidatively stable relative to nonfluorinated thioethers, suggesting the potential application of this unexplored functional group in biological probes and therapeutic agents.

Product Details of 99-61-6. Bye, fridends, I hope you can learn more about C7H5NO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem