Tag: M.W=100-150

Name: 2-Aminobenzamide. In 2019 MOLECULES published article about SELECTIVE PDE5 INHIBITOR; DRUG-LIKE; ORGANIC-SYNTHESIS; TETRAHYDROPROTOBERBERINE DERIVATIVES; GOLD(I)-CATALYZED CASCADE; REGIOSELECTIVE SYNTHESIS; PRIVILEGED STRUCTURES; TANDEM REACTION; CHEMICAL SPACE; EFFICIENT in [Jia, Xiuwen; Li, Pinyi; Liu, Xiaoyan; Lin, Jiafu; Chu, Yiwen; Zhao, Fei] Chengdu Univ, Sichuan Ind Inst Antibiot, Antibiot Res & Reevaluat Key Lab Sichuan Prov, Chengdu 610052, Sichuan, Peoples R China; [Yu, Jinhai] Univ Jinan, Sch Biol Sci & Technol, Jinan 250022, Shandong, Peoples R China; [Wang, Jiang; Liu, Hong] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; [Wang, Jiang; Liu, Hong] Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China; [Wang, Jiang; Liu, Hong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China in 2019, Cited 69. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.

The present study describes an AuPPh3Cl/AgSbF6-catalyzed cascade reaction between amine nucleophiles and alkynoic acids in water. This process proceeds in high step economy with water as the sole coproduct, and leads to the generation of two rings, together with the formation of three new bonds in a single operation. This green cascade process exhibits valuable features such as low catalyst loading, good to excellent yields, high efficiency in bond formation, excellent selectivity, great tolerance of functional groups, and extraordinarily broad substrate scope. In addition, this is the first example of the generation of an indole/thiophene/pyrrole/pyridine/naphthalene/benzene-fused N-heterocycle library through gold catalysis in water from readily available materials. Notably, the discovery of antibacterial molecules from this library demonstrates its high quality and potential for the identification of active pharmaceutical ingredients.

Name: 2-Aminobenzamide. Welcome to talk about 88-68-6, If you have any questions, you can contact Jia, XW; Li, PY; Liu, XY; Lin, JF; Chu, YW; Yu, JH; Wang, J; Liu, H; Zhao, F or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 2-Aminobenzamide. Authors Yang, L; Hou, HQ; Li, L; Wang, J; Zhou, SY; Wu, M; Ke, F in ROYAL SOC CHEMISTRY published article about in [Yang, Li; Li, Lan; Ke, Fang] Yibin Univ, Coll Chem & Chem Engn, Yibin, Sichuan, Peoples R China; [Hou, Huiqing; Wang, Jin; Zhou, Sunying; Wu, Mei; Ke, Fang] Fujian Med Univ, Fuzhou, Fujian, Peoples R China in 2021, Cited 64. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

An efficient and practical electrochemically catalyzed transition metal-free process for the synthesis of substituted quinazolinones from simple and readily available o-aminobenzonitriles and aldehydes in water has been accomplished. I-2/base and water play an unprecedented and vital role in the reaction. By electrochemically catalysed hydrolysis of o-aminobenzonitriles, the synthesis of quinazolinones with benzaldehyde was first proposed. The synthetic utility of this method was demonstrated by gram-scale operation, as well as the preparation of bioactive N-(2,5-dichlorophenyl)-6-(2,2,2-trifluoroethoxy) pteridin-4-amine, which enables straightforward, practical and environmentally benign quinazolinone formation.

Welcome to talk about 88-68-6, If you have any questions, you can contact Yang, L; Hou, HQ; Li, L; Wang, J; Zhou, SY; Wu, M; Ke, F or send Email.. Recommanded Product: 2-Aminobenzamide

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Parveen, I; Ahmed, N in [Parveen, Iram; Ahmed, Naseem] Indian Inst Technol Roorkee, Dept Chem, Roorkee 247667, Uttar Pradesh, India published A Route to Highly Functionalized Stereospecific trans -Aminated Aurones from 3-Bromoflavones with Aniline and N -Phenylurea via a Domino Aza-Michael Ring Opening and Cyclization Reactions in 2019.0, Cited 36.0. Formula: C7H8N2O. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8.

A facile cascade reaction is reported via aza-Michael addition, ring opening, and cyclization between 3-bromoflavone and aniline derivatives or N -phenylurea in the presence of KO t -Bu and CuI in DMF under mild reaction conditions. Products were obtained as stereospecific trans -aminated aurones in good to excellent yields (61-83%). Our protocol is operationally successful with ease, avoids the requirement of additives and ligands, and offers broad substrate scope.

Welcome to talk about 64-10-8, If you have any questions, you can contact Parveen, I; Ahmed, N or send Email.. Formula: C7H8N2O

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

HPLC of Formula: C7H8N2O. In 2019 J ENZYM INHIB MED CH published article about DIKETO ACID-DERIVATIVES; INTERFERENCE COMPOUNDS PAINS; DRUG-RESISTANCE MUTATIONS; REVERSE-TRANSCRIPTASE; RNASE-H; ACTIVE-SITE; DUAL INHIBITORS; MOLECULAR MECHANICS; COLORIMETRIC ASSAY; RNA/DNA HYBRID in [Massari, Serena; Desantis, Jenny; Sabatini, Stefano; Manfroni, Giuseppe; Felicetti, Tommaso; Cecchetti, Violetta; Tabarrini, Oriana] Univ Perugia, Dept Pharmaceut Sci, I-06123 Perugia, Italy; [Corona, Angela; Distinto, Simona; Caredda, Alessia; Maccioni, Elias; Tramontano, Enzo] Univ Cagliari, Dept Life & Environm Sci, Cittadella Univ Monserrato, I-09042 Cagliari, Italy; [Desantis, Jenny] Univ Perugia, Dept Chem Biol & Biotechnol, Perugia, Italy; [Pannecouque, Christophe] Katholieke Univ Leuven, Lab Virol & Chemotherapy, Rega Inst Med Res, Leuven, Belgium; [Tramontano, Enzo] CNR, Ist Ric Genet & Biomed, Monserrato, Italy in 2019, Cited 75. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.

The paper focussed on a step-by-step structural modification of a cycloheptathiophene-3-carboxamide derivative recently identified by us as reverse transcriptase (RT)-associated ribonuclease H (RNase H) inhibitor. In particular, its conversion to a 2-aryl-cycloheptathienoozaxinone derivative and the successive thorough exploration of both 2-aromatic and cycloheptathieno moieties led to identify oxazinone-based compounds as new anti-RNase H chemotypes. The presence of the catechol moiety at the C-2 position of the scaffold emerged as critical to achieve potent anti-RNase H activity, which also encompassed anti-RNA dependent DNA polymerase (RDDP) activity for the tricyclic derivatives. Benzothienooxazinone derivative 22 resulted the most potent dual inhibitor exhibiting IC(50)s of 0.53 and 2.90 mu M against the RNase H and RDDP functions. Mutagenesis and docking studies suggested that compound 22 binds two allosteric pockets within the RT, one located between the RNase H active site and the primer grip region and the other close to the DNA polymerase catalytic centre. [GRAPHICS] .

HPLC of Formula: C7H8N2O. Welcome to talk about 88-68-6, If you have any questions, you can contact Massari, S; Corona, A; Distinto, S; Desantis, J; Caredda, A; Sabatini, S; Manfroni, G; Felicetti, T; Cecchetti, V; Pannecouque, C; Maccioni, E; Tramontano, E; Tabarrini, O or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2019.0 MICROCHIM ACTA published article about PERFORMANCE LIQUID-CHROMATOGRAPHY; ENVIRONMENTAL WATER; GAS-CHROMATOGRAPHY; MILK SAMPLES; MICROEXTRACTION; SPECTROMETRY; CARBON; DIURON; BIOSENSORS; IONS in [Guo, Liying; Hao, Lin; Gao, Tian; Wang, Chun; Wu, Qiuhua; Wang, Zhi] Hebei Agr Univ, Dept Chem, Coll Sci, Baoding 071001, Peoples R China in 2019.0, Cited 34.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8. Formula: C7H8N2O

Graphene oxide was covalently modified with p-phenylenediamine via a diazonium reaction. The resulting material was employed as a sorbent for the solid-phase extraction of six phenylurea herbicides (metoxuron, monuron, chlortoluron, isoproturon, monolinuron, and buturon) from environmental water and lettuce leafs. Some key factors that influence the extraction efficiency were studied, including sample loading rate, sample pH, and desorption conditions. Following desorption with acetonitrile, the analytes were quantified by HPLC with UV detection. Under optimized conditions, response to phenylurea herbicides is linear in the 2.0-100ngmL(-1) concentration range for water samples, and 5.0-100ngg(-1) for leaf lettuces. The limits of detection are 0.10-0.25ngmL(-1) for water samples, and 1.5-2.5ngg(-1) for leaf lettuces. The sorbent was also applied to the preconcentration of organic compounds including nitroimidazoles, chlorophenols, phenylurea insecticides and phthalates. This shows that this sorbent has a large potential for the enrichment of organic pollutants.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry very interesting. Saw the article ompg-C3N4/SO3H: an efficient and recyclable organocatalyst for the facile synthesis of 2,3-dihydroquinazolin-4(1H)-ones published in 2019. Application In Synthesis of 2-Aminobenzamide, Reprint Addresses Ghafuri, H (corresponding author), Iran Univ Sci & Technol, Dept Chem, Catalysts & Organ Synth Res Lab, Tehran 1684613114, Iran.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

In the present work, sulfonated highly ordered mesoporous graphitic carbon nitride (ompg-C3N4/SO3H) was synthesized successfully and employed as an efficient and reusable heterogeneous solid acid catalyst for the rapid and one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones via the condensation of anthranilamide with aldehydes or ketones in good to excellent yields. The organocatalyst was characterized by Fourier transform infrared spectroscopy, X-ray diffraction, field emission scanning electron microscopy, energy-dispersive X-ray spectrometer, Brunauer-Emmett-Teller surface area, and thermal gravimetric and differential thermal analysis. The substantial advantages of this procedure involve short reaction times, high catalytic activity, easy workup, high purity of the products, and easy recovery and reusability of the catalyst.

Application In Synthesis of 2-Aminobenzamide. Welcome to talk about 88-68-6, If you have any questions, you can contact Ghafuri, H; Goodarzi, N; Rashidizadeh, A; Fard, MAD or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about METAL-ORGANIC FRAMEWORKS; ONE-POT SYNTHESIS; TERMINAL ALKYNES; TANDEM SYNTHESIS; 2-AMINOBENZAMIDES; COMPOSITE; AMINATION; CHEMISTRY; ACIDS, Saw an article supported by the UGCUniversity Grants Commission, India; Science and Engineering Research Board (SERB), New Delhi, India [SR/FT/CS-53/2011]; University Grants Commission, New Delhi, India (UGC)University Grants Commission, India [42-291/2013(SR)]; Council for Scientific and Industrial Research, New Delhi, India (CSIR) [02(0191)14/EMR-II]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Latha, G; Devarajan, N; Suresh, P. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide. Name: 2-Aminobenzamide

A benign and straightforward method to access quinazolinones have been developed using easily preparable Cu-3(BTC)(2)MOF as a sustainable solid-Lewis acid catalyst under mild condition. Cu-3(BTC)(2)MOF was prepared and characterized using various analytical tools such as PXRD, FT-IR, SEM, TGA, and ICP-OES. Synthesis of the quinazolinone is catalyzed by the presence of coordinatively unsaturated open Cu(II)sites in Cu-3(BTC)(2)MOF using renewable ethanol as a solvent with minimum copper loading (0.07 mmol) without any harsh reaction condition. A series of substituted quinazolinones were synthesized with good to excellent yields. The efficiency of the present framework copper catalysts was rationalized by comparing with other MOFs and homogeneous catalytic systems. The stability of the catalyst was demonstrated by six consecutive runs and heterogeneity test, which was also evidenced from the technical supports such as PXRD, FT-IR and SEM analyses of the recovered catalyst.

Name: 2-Aminobenzamide. Welcome to talk about 88-68-6, If you have any questions, you can contact Latha, G; Devarajan, N; Suresh, P or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 2-Aminobenzamide. Mondal, MA; Mondal, S; Khan, AA in [Mondal, Mohabul A.; Mondal, Sudipta; Khan, Abdul A.] Jadavpur Univ, Dept Chem, Kolkata 700032, W Bengal, India published A mechanistic insight into the acid catalyzed, one-pot synthesis of isoindole-fused quinazolin 4-ones in 2020, Cited 11. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.

One-pot synthesis of isoindole fused quinazolin 4-ones via intramolecular 1,3 hydride transfer in the presence of acid catalyst has been described. Substrate scope and mechanistic insights were investigated. Substituents on the amide side have a negligible influence on the key step and therefore the method have wide scope for accessing various bicyclic core structure.

Recommanded Product: 2-Aminobenzamide. Welcome to talk about 88-68-6, If you have any questions, you can contact Mondal, MA; Mondal, S; Khan, AA or send Email.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Kalogirou, AS; Kourtellaris, A; Koutentis, PA in WILEY-V C H VERLAG GMBH published article about ANTIFUNGAL ACTIVITY; MOLECULAR DOCKING; DERIVATIVES; CHEMISTRY; 3,4,4,5-TETRACHLORO-4H-1,2,6-THIADIAZINE; CYCLOPENTATHIADIAZINES; TETRACYANOETHYLENE; SUBSTITUTION; ACCESS; SPIRO in [Kalogirou, Andreas S.] European Univ Cyprus, Dept Life Sci, 6 Diogenis Str,POB 22006, CY-1516 Nicosia, Cyprus; [Kalogirou, Andreas S.; Kourtellaris, Andreas; Koutentis, Panayiotis A.] Univ Cyprus, Dept Chem, POB 20537, CY-1678 Nicosia, Cyprus in 2019, Cited 47. COA of Formula: C7H8N2O. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

A three-step synthesis of 3 ‘,5 ‘-dichloro-1H-spiro(quinazo-line-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones starting from 3,4,4,5-tetra-chloro-4H-1,2,6-thiadiazine is presented. The latter reacts with 2-aminobenzonitriles to give 2-[(3,5-dichloro-4H-1,2,6-thiadiazin-4-ylid-ene)amino]benzonitriles, which affords, after hydration, the respective benzamides. Upon heating at reflux in EtOH or HFIP, the benzamides intramolecularly cyclize onto the thiadiazine C4 position to give 3 ‘,5 ‘-dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones. Single crystal X-ray crystallography supports the structure of two analogues. The chloride displacement of these new spiroquinazolinones was demonstrated by Stille coupling, and by reaction with methoxide to afford both the mono and bis-methoxy derivatives.

Welcome to talk about 88-68-6, If you have any questions, you can contact Kalogirou, AS; Kourtellaris, A; Koutentis, PA or send Email.. COA of Formula: C7H8N2O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Olguin, CJM; Sampaio, SC; dos Reis, RR; Remor, MB; Olguin, CFA in TAYLOR & FRANCIS LTD published article about HYDROPHOBIC ORGANIC-CHEMICALS; DIFFERENT VALIDATION CRITERIA; REAL EXTERNAL PREDICTIVITY; QSAR MODELS; RATIONAL SELECTION; REGRESSION-MODELS; K-OC; PESTICIDES; SEDIMENTS; DATASETS in [Olguin, C. J. M.; Sampaio, S. C.; dos Reis, R. R.; Remor, M. B.] Western Parana State Univ, Grad Program Agr Engn PGEAGRI, Agroenvironm Sci Res Grp, Cascavel, Parana, Brazil; [Olguin, C. F. A.] Western Parana State Univ, Dept Chem, Toledo, Parana, Brazil in 2019.0, Cited 37.0. Quality Control of 1-Phenylurea. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

Quantitative structure-property relationship (QSPR) modelling has been used in many scientific fields. This approach has been extensively applied in environmental research to predict physicochemical properties of compounds with potential environmental impact. The soil sorption coefficient is an important parameter for the evaluation of environmental risks, and it helps to determine the final fate of substances in the environment. In the last few years, different QSPR models have been developed for the determination of the sorption coefficient. In this study, several QSPR models were generated and evaluated for the prediction of log K-oc from the relationship with log P. These models were obtained from an extensive and diverse training set (n = 639) and from subsets of this initial set (i.e. halves, fourths and eighths). The aim of this study was to investigate whether the size of the training set affects the statistical quality of the obtained models. Furthermore, statistical equivalence was verified between the models obtained from smaller sets and the model obtained from the total training set. The results confirmed the equivalence between the models, thus indicating the possibility of using smaller training sets without compromising the statistical quality and predictive capability, as long as most chemical classes in the test set are represented in the training set.

Welcome to talk about 64-10-8, If you have any questions, you can contact Olguin, CJM; Sampaio, SC; dos Reis, RR; Remor, MB; Olguin, CFA or send Email.. Quality Control of 1-Phenylurea

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem