Tag: M.W=100-150

An article Real-life results from the overall population and key subgroups within the Italian cohort of nivolumab expanded access program in non-squamous non-small cell lung cancer WOS:000499645600008 published article about BRAIN METASTASES; DOCETAXEL; PEMBROLIZUMAB; INHIBITORS in [Grossi, Francesco] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Med Oncol Unit, Milan, Italy; [Genova, Carlo] IRCCS Osped Policlin San Martino, Lung Canc Unit, Genoa, Italy; [Crino, Lucio; Delmonte, Angelo] Ist Sci Romagnolo Studio & Cura Tumori IRST IRCCS, Dept Med Oncol, Meldola, Italy; [Turci, Daniele] Osped S Maria Delle Croci, Med Oncol Unit, Ravenna, Italy; [Signorelli, Diego] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy; [Passaro, Antonio] European Inst Oncol IRCCS, IEO, Div Thorac Oncol, Milan, Italy; [Parra, Hector Soto] Azienda Osped Univ AOU Policlin Vittorio Emanuele, Dept Oncol, Catania, Italy; [Catino, Annamaria] IRCCS Ist Tumori Giovanni Paolo II, Med Oncol Unit, Patol Torac, Bari, Italy; [Landi, Lorenza] AUSL Romagna, Dept Hematol Oncol, Ravenna, Italy; [Gelsomino, Francesco] AOU Policlin St Orsola Malpighi, Oncol Unit, Bologna, Italy; [Tiseo, Marcello] Univ Parma, Dept Med & Surg, Parma, Italy; [Tiseo, Marcello] Azienda Osped Univ Parma, Oncol Med, Parma, Italy; [Puppo, Gianfranco] Osped Macerata, Pulmonol Unit, Macerata, Italy; [Roila, Fausto] Osped S Maria Misericordia, Med Oncol Unit, Perugia, Italy; [Ricciardi, Serena] Azienda Osped San Camillo Forlanini, Pulm Oncol Unit, Rome, Italy; [Tonini, Giuseppe] Univ Campus Biomed, Dept Oncol, Rome, Italy; [Cognetti, Francesco] Univ Roma La Sapienza, Ist Nazl Tumori Regina Elena, Med Oncol Unit, Rome, Italy; [Toschi, Luca] IRCCS Ist Clin Humanitas, Dept Hematol Oncol, Rozzano, Italy; [Tassinari, Davide] AUSL Romagna, Oncol Unit, Rimini, Italy; [Scoppola, Alessandro] Ist Dermopat Immacolata, Dept Med Oncol, Rome, Italy; [Giannarelli, Diana] Ist Nazl Tumori Regina Elena, BIostat, Rome, Italy; [Cortesi, Enrico] Policlin Umberto 1, Oncol Unit, Rome, Italy in 2019.0, Cited 19.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8. Application In Synthesis of 1-Phenylurea

Background: Nivolumab was the first immune checkpoint inhibitor approved for previously treated advanced nonesmall cell lung cancer (NSCLC). Before its introduction in the market, nivolumab was made available to NSCLC patients through an expanded access program (EAP). Here we present the Italian cohort of patients with non-squamous NSCLC enrolled in a worldwide nivolumab EAP, with subgroup analyses involving elderly patients, patients with central nervous system (CNS) metastases and patients receiving nivolumab beyond progression. Methods: Pretreated patients with advanced non-squamous NSCLC received nivolumab at 3 mg/kg every 2 weeks up to 24 months. Efficacy data (investigator-assessed tumour response, progression date and survival) and safety data were collected. Findings: 1588 patients were treated across 153 Italian centres. Overall response rate and disease control rate were 18% and 44%, respectively; median overall survival (OS) was 11.3 months (95% CI: 10.2-12.4). Elderly patients (>= 70 n = 522; >= 75 n = 232) achieved outcomes similar to the global study population; patients with CNS metastases (n = 409) had an OS of 8.6 months (95% CI: 6.4-10.8), and a 1-year OS rate of 43%. Nivolumab was administered beyond progression to 276 patients (26%), 57 of whom achieved subsequent disease control; the median OS of patients receiving nivolumab beyond progression was 16.2 months (95% CI: 14.0-18.4), while 1-year OS rate was 62%. Interpretation: To date, this is the largest clinical experience with nivolumab in a real-world setting. Our data support its use in clinical practice for pretreated non-squamous NSCLC, including patients with older age or CNS metastases. (C) 2019 Elsevier Ltd. All rights reserved.

Welcome to talk about 64-10-8, If you have any questions, you can contact Grossi, F; Genova, C; Crino, L; Delmonte, A; Turci, D; Signorelli, D; Passaro, A; Parra, HS; Catino, A; Landi, L; Gelsomino, F; Tiseo, M; Puppo, G; Roila, F; Ricciardi, S; Tonini, G; Cognetti, F; Toschi, L; Tassinari, D; Scoppola, A; Giannarelli, D; Cortesi, E or send Email.. Application In Synthesis of 1-Phenylurea

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Zheng, Y; Hou, P; Li, Y; Sun, JW; Cui, HX; Zhang, HY; Chen, S in MDPI published article about in [Zheng, Yan; Zhang, Haiyan] Qiqihar Med Univ, Sci Res Dept, Qiqihar 161006, Peoples R China; [Hou, Peng; Li, Yu; Sun, Jingwen; Cui, Hongxia; Chen, Song] Qiqihar Med Univ, Coll Pharm, Qiqihar 161006, Peoples R China in 2021, Cited 36. Recommanded Product: 88-68-6. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

Due to the redox properties closely related to numerous physiological and pathological processes, biothiols, including cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), have received considerable attention in biological science. On account of the important physiological roles of these biothiols, it is of profound significance to develop sensitive and selective detection of biothiols to understand their biological profiles. In this work, we reported an efficient fluorescent probe, PHPQ-SH, for detecting biothiols in vitro and vivo, based on the phenothiazine-HPQ skeleton, with DNBS (2,4-dinitrobenzenesulfonate) as the response unit. Probe PHPQ-SH exhibited brilliant sensing performances toward thiols, including a large Stokes shift (138 nm), excellent sensitivity (for GSH, LOD = 18.3 nM), remarkable fluorescence enhancement (163-fold), low cytotoxicity, rapid response (8 min), and extraordinary selectivity. Finally, the probe PHPQ-SH illustrated herein was capable of responding and visualizing biothiols in MCF-7 cells and zebrafish.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Khan, D; Ahmed, N; Alsharif, MA; Alahmdi, MI; Mukhtar, S in WILEY-V C H VERLAG GMBH published article about ONE-POT SYNTHESIS; HIGHLY EFFICIENT; BENZYL ALCOHOLS; METHYL KETONES; BENZIMIDAZOLES; QUINAZOLINONES; BENZOXAZOLES; AMINATION; IODINE; FACILE in [Khan, Danish; Ahmed, Naseem] Indian Inst Technol Roorkee, Dept Chem, Roorkee 247667, Uttarakhand, India; [Alsharif, Meshari A.; Alahmdi, Mohammed Issa; Mukhtar, Sayeed] Univ Tabuk, Fac Sci, Dept Chem, Tabuk 71491, Saudi Arabia in 2019, Cited 66. Category: thiomorpholine. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

An interestingcyclization reactions of aryl ketones with 2-amino aniline derivatives under SeO2 (oxidant) are described for the synthesis of benzoxazole, benzothiazole, benzimidazole and quinazolinone through the C-C cleavage of acetophenone. The reaction likely involves sequential C-N, C-O and C-S bond formation followed by C(CO)-C(alkyl) bond cleavage. Various substituted fused heterocycles are obtained in good to excellent (gram scale) yields in a single step from readily available acetophenones.

Category: thiomorpholine. About 2-Aminobenzamide, If you have any questions, you can contact Khan, D; Ahmed, N; Alsharif, MA; Alahmdi, MI; Mukhtar, S or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Formula: C7H8N2O. I found the field of Chemistry very interesting. Saw the article Synthesis of quinazolin-4(3H)-ones via electrochemical decarboxylative cyclization of alpha-keto acids with 2-aminobenzamides published in 2021, Reprint Addresses Zhang, JL; Xu, L; Wei, Y (corresponding author), Shihezi Univ, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Sch Chem & Chem Engn, Shihezi 832003, Peoples R China.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide.

Herein, an environmentally benign electrochemical protocol has been disclosed for the synthesis of quinazolin-4 (3H)-one derivatives from readily available alpha-keto acids and 2-aminobenzamides. This decarboxylative cyclization process proceeds conveniently in the absence of any homogeneous metal catalysts, bases, or external oxidants. This protocol also features CO2 by-products, mild reaction conditions (room temperature and air atmosphere), and a wide variety of substrate scope, including an array of 2,3-disubstituted quinazolinone products.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 1-Phenylurea. In 2019.0 CHEMSUSCHEM published article about POLYMERIC PHOTOCATALYST; H-2 PRODUCTION; ORGANIC-DYES; NANOSHEETS; G-C3N4; WATER; SEMICONDUCTORS; ABSORPTION; CONSTRUCTION; FLUORINATION in [Sun, Zongzhao] Harbin Inst Technol, Sch Chem & Chem Engn, Harbin 150001, Heilongjiang, Peoples R China; [Sun, Zongzhao; Jiang, Yabin; Zeng, Lei; Huang, Limin] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China in 2019.0, Cited 80.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8.

Inspired by donor-acceptor (D-A) polymers in organic solar cell and the extended conjugation effect, a conceptual design of D–A-type mesoporous carbon nitride with benzene or thiophene as a -spacer is proposed as an efficient photocatalyst for hydrogen evolution. The photocatalyst was successfully synthesized by a one-pot thermopolymerization based on nucleophilic substitution and a Schiff-base chemical reaction. On the molecular level, the insertion of an in-plane benzene as a -spacer by forming covalent bonds C=N (acceptor) and C-N (donor) interrupts the continuity of tri-s-triazine units and maintains the intrinsic – conjugated electronic system. Synchronously, the enlarged electron delocalization and the intramolecular charge transfer induced by polarization provide force-directed migration of electrons, leading to boosted optical absorption capability and enhanced photogenerated carrier separation. With the synergistic effects of the mesoporous structure and excellent optical and electronic properties, a fivefold increase in the H-2 evolution rate compared with that of pristine g-C3N4 was achieved with robust performance. In addition, other simple aromatic heterocyclic compounds (e.g., pyridine, thiophene and furan)-based D–A structures with a higher hydrogen evolution rate (up to sevenfold increase) were also explored to broaden the application for the design of novel photocatalysts.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis WOS:000629336800015 published article about MULTICENTER PHASE-II; BREQUINAR SODIUM; IMMUNOSUPPRESSIVE DRUG; PLASMODIUM-FALCIPARUM; PYRIMIDINE SYNTHESIS; DHODH; VIDOFLUDIMUS; LEFLUNOMIDE; DISCOVERY; BLOCKADE in [Zeng, Fanxun; Yang, Guantian; Zhang, Letian; Xu, Xiaoyong] East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China; [Li, Shiliang; Luo, Yating; Qi, Tiantian; Liang, Yingfan; Yang, Tingyuan; Wang, Rui; Zhu, Lili; Li, Honglin] East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China in 2021, Cited 62. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6. COA of Formula: C7H8N2O

Human dihydroorotate dehydrogenase (DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases, such as rheumatoid arthritis (RA), psoriasis and multiple sclerosis (MS). Herein, a series of acrylamide-based novel DHODH inhibitors as potential RA treatment agents were designed and synthesized. 2-Acrylamidobenzoic acid analog 11 was identified as the lead compound for structure-activity relationship (SAR) studies. The replacement of the phenyl group with naphthyl moieties improved inhibitory activity significantly to double-digit nanomolar range. Further structure optimization revealed that an acrylamide with small hydrophobic groups (Me, Cl or Br) at the 2-position was preferred. Moreover, adding a fluoro atom at the 5-position of the benzoic acid enhanced the potency. The optimization efforts led to potent compounds 42 and 53.55 with IC50 values of 41, 44, 32, and 42 nmol/L, respectively. The most potent compound 54 also displayed favorable pharmacokinetic (PK) profiles and encouraging in vivo anti-arthritic effects in a dose-dependent manner. (C) 2021 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

COA of Formula: C7H8N2O. Welcome to talk about 88-68-6, If you have any questions, you can contact Zeng, FX; Li, SL; Yang, GT; Luo, YT; Qi, TT; Liang, YF; Yang, TY; Zhang, LT; Wang, R; Zhu, LL; Li, HL; Xu, XY or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Formula: C7H8N2O. Grossi, F; Genova, C; Crino, L; Delmonte, A; Turci, D; Signorelli, D; Passaro, A; Parra, HS; Catino, A; Landi, L; Gelsomino, F; Tiseo, M; Puppo, G; Roila, F; Ricciardi, S; Tonini, G; Cognetti, F; Toschi, L; Tassinari, D; Scoppola, A; Giannarelli, D; Cortesi, E in [Grossi, Francesco] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Med Oncol Unit, Milan, Italy; [Genova, Carlo] IRCCS Osped Policlin San Martino, Lung Canc Unit, Genoa, Italy; [Crino, Lucio; Delmonte, Angelo] Ist Sci Romagnolo Studio & Cura Tumori IRST IRCCS, Dept Med Oncol, Meldola, Italy; [Turci, Daniele] Osped S Maria Delle Croci, Med Oncol Unit, Ravenna, Italy; [Signorelli, Diego] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy; [Passaro, Antonio] European Inst Oncol IRCCS, IEO, Div Thorac Oncol, Milan, Italy; [Parra, Hector Soto] Azienda Osped Univ AOU Policlin Vittorio Emanuele, Dept Oncol, Catania, Italy; [Catino, Annamaria] IRCCS Ist Tumori Giovanni Paolo II, Med Oncol Unit, Patol Torac, Bari, Italy; [Landi, Lorenza] AUSL Romagna, Dept Hematol Oncol, Ravenna, Italy; [Gelsomino, Francesco] AOU Policlin St Orsola Malpighi, Oncol Unit, Bologna, Italy; [Tiseo, Marcello] Univ Parma, Dept Med & Surg, Parma, Italy; [Tiseo, Marcello] Azienda Osped Univ Parma, Oncol Med, Parma, Italy; [Puppo, Gianfranco] Osped Macerata, Pulmonol Unit, Macerata, Italy; [Roila, Fausto] Osped S Maria Misericordia, Med Oncol Unit, Perugia, Italy; [Ricciardi, Serena] Azienda Osped San Camillo Forlanini, Pulm Oncol Unit, Rome, Italy; [Tonini, Giuseppe] Univ Campus Biomed, Dept Oncol, Rome, Italy; [Cognetti, Francesco] Univ Roma La Sapienza, Ist Nazl Tumori Regina Elena, Med Oncol Unit, Rome, Italy; [Toschi, Luca] IRCCS Ist Clin Humanitas, Dept Hematol Oncol, Rozzano, Italy; [Tassinari, Davide] AUSL Romagna, Oncol Unit, Rimini, Italy; [Scoppola, Alessandro] Ist Dermopat Immacolata, Dept Med Oncol, Rome, Italy; [Giannarelli, Diana] Ist Nazl Tumori Regina Elena, BIostat, Rome, Italy; [Cortesi, Enrico] Policlin Umberto 1, Oncol Unit, Rome, Italy published Real-life results from the overall population and key subgroups within the Italian cohort of nivolumab expanded access program in non-squamous non-small cell lung cancer in 2019.0, Cited 19.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8.

Background: Nivolumab was the first immune checkpoint inhibitor approved for previously treated advanced nonesmall cell lung cancer (NSCLC). Before its introduction in the market, nivolumab was made available to NSCLC patients through an expanded access program (EAP). Here we present the Italian cohort of patients with non-squamous NSCLC enrolled in a worldwide nivolumab EAP, with subgroup analyses involving elderly patients, patients with central nervous system (CNS) metastases and patients receiving nivolumab beyond progression. Methods: Pretreated patients with advanced non-squamous NSCLC received nivolumab at 3 mg/kg every 2 weeks up to 24 months. Efficacy data (investigator-assessed tumour response, progression date and survival) and safety data were collected. Findings: 1588 patients were treated across 153 Italian centres. Overall response rate and disease control rate were 18% and 44%, respectively; median overall survival (OS) was 11.3 months (95% CI: 10.2-12.4). Elderly patients (>= 70 n = 522; >= 75 n = 232) achieved outcomes similar to the global study population; patients with CNS metastases (n = 409) had an OS of 8.6 months (95% CI: 6.4-10.8), and a 1-year OS rate of 43%. Nivolumab was administered beyond progression to 276 patients (26%), 57 of whom achieved subsequent disease control; the median OS of patients receiving nivolumab beyond progression was 16.2 months (95% CI: 14.0-18.4), while 1-year OS rate was 62%. Interpretation: To date, this is the largest clinical experience with nivolumab in a real-world setting. Our data support its use in clinical practice for pretreated non-squamous NSCLC, including patients with older age or CNS metastases. (C) 2019 Elsevier Ltd. All rights reserved.

Formula: C7H8N2O. Bye, fridends, I hope you can learn more about C7H8N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Pharmacology & Pharmacy very interesting. Saw the article Design, synthesis and biological evaluation of novel thioquinazolinone-based 2-aminobenzamide derivatives as potent histone deacetylase (HDAC) inhibitors published in 2019. Product Details of 88-68-6, Reprint Addresses Yuan, QP (corresponding author), Beijing Univ Chem Technol, Coll Life Sci & Technol, Minist Educ, Key Lab Biomed Mat Nat Macromol, 15 Beisanhuan East Rd, Beijing 100029, Peoples R China.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

A series of novel 2-aminobenzamide derivatives decorated with thioquinazolinone were designed and synthesized as histone deacetylase (HDAC) inhibitors. These derivatives were evaluated for their anti-proliferative activities against several human cancer cell lines including A375, Hela, A549, HCT116 and SMMC7721. It’s significantly indicated that some inhibitors exhibited potent antiproliferative activities towards all the studied cancer cell lines. Compounds 7a, 4i, 4o, and 4p exhibited higher antiproliferative activities towards three cancer cell lines: A375, A549 and SMMC7721 compared to CS055, MS275, and C1994. Compound 4p showed more than 4000-fold the isoform selectivity for HDACI and more than 250-fold selectivity for HDAC2 compared with HDAC6. The molecular docking analysis reasonably explained the HDAC inhibitory activity and isoform selectivity. In addition, compounds 7a, 4i, 4o, and 4p showed potent inhibitory activities in migration assay and colony formation analysis, and also promoted cell apoptosis. Moreover, compounds 7a, 4i, and 4o inhibited the growth of SMMC7721 cells at S phase of the cell cycle. The immunofluorometric analysis indicated that compounds 7a, 4i, 4o, and 4p could increase the acetylation status of H3K9. Furthermore, in vivo anticancer efficacy of compound 4p was assessed in the A549 xenograft models, and 4p demonstrated potent antitumor activity (TGI = 62.5%). This study provided an effective strategy for further development of tumor-targeting therapy. (C) 2019 Elsevier Masson SAS. All rights reserved.

Product Details of 88-68-6. Bye, fridends, I hope you can learn more about C7H8N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Formula: C7H8N2O. Authors Thorve, PR; Maji, B in ROYAL SOC CHEMISTRY published article about in [Thorve, Pradip Ramdas; Maji, Biplab] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, India in 2021, Cited 72. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

Herein, we report a bioinspired catalytic system for the one-pot cascade oxidation of a native primary amine and an in situ generated non-native secondary amine. The catalyst consists of an o-quinone cofactor phd (1,10-phenanthroline-5,6-dione) and a copper ion and operates under ambient air conditions. Quinazolin-4(3H)-ones, which are common pharmacophores present in numerous pharmaceuticals and bioactive compounds, were synthesized in high yields. A detailed kinetic and mechanistic study elucidates the role of the catalyst in the multi-step oxidative cascade reaction.

Welcome to talk about 88-68-6, If you have any questions, you can contact Thorve, PR; Maji, B or send Email.. Formula: C7H8N2O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about POSITRON-EMISSION-TOMOGRAPHY; IN-VIVO; AUTOMATED RADIOSYNTHESIS; MEDIATED SYNTHESIS; RECEPTOR AGONIST; PET; BIODISTRIBUTION; CARBONYLATION; RADIOLIGAND; LIGAND, Saw an article supported by the European Union (EU) through the project Radiochemistry for Molecular Imaging [EU FP7-PEOPLE-2012-ITN-RADIOMI]; Centre National de la Recherche Scientifique (CNRS)Centre National de la Recherche Scientifique (CNRS); Institut national de la sante et de la recherche medicale (INSERM)Institut National de la Sante et de la Recherche Medicale (Inserm); University of Lyon 1. COA of Formula: C7H8N2O. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Liger, F; Cadarossanesaib, F; Iecker, T; Tourvieille, C; Le Bars, D; Billard, T. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

Labeling of heterocycles with carbon-11 is generally performed through peripheral functionalizations and more scarcely inside heterocyclic core. Such less common approach usually requires preliminary multi-step synthesis of reactive species. Herein, a cyclization reaction by direct use of cyclotron-produced [C-11]CO2 is described to obtain various heterocycles intracyclically labeled in only 10 minutes.

COA of Formula: C7H8N2O. Welcome to talk about 88-68-6, If you have any questions, you can contact Liger, F; Cadarossanesaib, F; Iecker, T; Tourvieille, C; Le Bars, D; Billard, T or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem