Tag: M.W=100-150

Authors Boualia, I; Debache, A; Boulcina, R; Roisnel, T; Berree, F; Vidal, J; Carboni, B in PERGAMON-ELSEVIER SCIENCE LTD published article about NONCOVALENT INHIBITION; INDUCED HETEROARYLATION; PRIVILEGED SCAFFOLD; 20S PROTEASOME; CANCER; QUINOLINE; IDENTIFICATION; QUINAZOLINES; ALLOSTERY; TMC-95A in [Boualia, Imen; Debache, Abdelmadjid; Boulcina, Raouf] Univ Freres Mentouri Constantine, Lab Synthese Mol Interets Biol, Constantine 25000, Algeria; [Boualia, Imen; Roisnel, Thierry; Berree, Fabienne; Vidal, Joelle; Carboni, Bertrand] Univ Rennes, ISCR, CNRS, UMR 6226, F-35000 Rennes, France; [Boulcina, Raouf] Univ Mostefa Benboulaid Batna 2, Dept Sci & Tech, Fac Technol, Batna 05000, Algeria in 2020, Cited 45. Recommanded Product: 2-Aminobenzamide. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

A new series of 3-(quinazol-2-yl)-quinolines was synthesized by SNAr reaction from easily prepared 4-chloro-2-(2-chloroquinolin-3-yl)quinazolines and a range of phenols and thiophenol as nucleophiles. The AlCl3-mediated CC bond formation was also successfully exploited to introduce aryl and hereroaryl substituents on one or both heterocyclic units. These procedures afford efficient syntheses of polysubstituted 3-(quinazol-2-yl)-quinolines in few steps and high yields. Some of these polysubstituted 3-(quinazol-2-yl)-quinolines inhibit the human 20S proteasome. (C) 2020 Elsevier Ltd. All rights reserved.

Recommanded Product: 2-Aminobenzamide. About 2-Aminobenzamide, If you have any questions, you can contact Boualia, I; Debache, A; Boulcina, R; Roisnel, T; Berree, F; Vidal, J; Carboni, B or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Polystyrene-Supported Palladium (Pd@PS)-Catalyzed Carbonylative Annulation of Aryl Iodides Using Oxalic Acid as a Sustainable CO Source for the Synthesis of 2-Aryl Quinazolinones WOS:000494247100001 published article about CATALYZED OXIDATIVE SYNTHESIS; CASCADE SYNTHESIS; O-AMINOBENZAMIDES; N-HETEROCYCLES; LUOTONIN-A; QUINAZOLIN-4(3H)-ONES; DERIVATIVES; CYCLIZATION in [Ram, Shankar; Shaifali; Chauhan, Arvind Singh; Sheetal; Sharma, Ajay Kumar; Das, Pralay] CSIR Inst Himalayan Bioresource Technol, Nat Prod Chem & Proc Dev Div, Palampur 176061, Himachal Prades, India; [Ram, Shankar; Shaifali; Chauhan, Arvind Singh; Sheetal; Sharma, Ajay Kumar; Das, Pralay] CSIR IHBT, Acad Sci & Innovat Res, Palampur 176061, Himachal Prades, India in 2019, Cited 53. COA of Formula: C7H8N2O. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

An efficient and convenient strategy for the synthesis of diversely substituted quinazolinones from o-carbamoyl/cyano aniline and aryl iodides using oxalic acid as a CO source under polystyrene supported palladium (Pd@PS) nanoparticles (NPs) catalyzed conditions has been developed. In this study, oxalic acid has been employed as safe, economic, environmentally benign, sustainable and bench-stable, solid CO surrogate under Double-Layer-Vial (DLV) system for the synthesis of 2-aryl quinazolinones. This methodology does not require any special high-pressure equipment like autoclaves, microwaves, etc. Moreover, a simple procedure for catalyst preparation, catalyst recyclability, easy handling of reaction, additive and base-free generation of CO, excellent to good yields and vast substrate scope are the additional features of developed protocol.

About 2-Aminobenzamide, If you have any questions, you can contact Ram, S; Shaifali; Chauhan, AS; Sheetal; Sharma, AK; Das, P or concate me.. Product Details of 88-68-6

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry; Science & Technology – Other Topics very interesting. Saw the article Visible-light-mediated organoboron-catalysed metal-free dehydrogenation of N-heterocycles using molecular oxygen published in 2021. Name: 2-Aminobenzamide, Reprint Addresses Zhang, JL; Xu, L (corresponding author), Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China.. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

The surge of photocatalytic transformation not only provides unprecedented synthetic methods, but also triggers the enthusiasm for more sustainable photocatalysts. On the other hand, oxygen is an ideal oxidant in terms of atom economy and environmental friendliness. However, the poor reactivity of oxygen at the ground state makes its utilization challenging. Herein, a visible-light-induced oxidative dehydrogenative process is disclosed, which uses an organoboron compound as the photocatalyst and molecular oxygen as the sole oxidant. Via this approach, an array of N-heterocycles have been accessed under metal-free mild conditions, in good to excellent yields.

Name: 2-Aminobenzamide. About 2-Aminobenzamide, If you have any questions, you can contact Wei, LF; Wei, Y; Zhang, JL; Xu, L or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Agriculture; Food Science & Technology very interesting. Saw the article Glucose and insulin responses to an intravenous glucose tolerance test administered to feed-restricted dairy cows receiving folic acid and vitamin B-12 supplements published in 2019.0. Formula: C7H8N2O, Reprint Addresses Girard, CL (corresponding author), Agr & Agroalimentaire Canada, Ctr Rech & Dev Sherbrooke, Sherbrooke, PQ J1M 0C8, Canada.. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea

The present experiment was conducted to determine whether, during periods of negative energy balance, the increase in glucose availability, despite similar DMI and greater milk production, induced by a combined supplement of folic acid and vitamin B-12 was related to effects of insulin on metabolism. Sixteen multiparous Holstein cows averaging 45 days in milk (standard deviation: 3) were assigned to 8 blocks of 2 animals each according to their milk production (45 kg/d; standard deviation: 6) during the week preceding the beginning of the experiment. Within each block, they received weekly intramuscular injections of either saline (CON) or folic acid and vitamin B-12 (VIT) during 5 consecutive weeks. During the last week, the cows were fed 75% of their ad libitum intake during 4 d. Blood samples were taken the morning before starting the feed restriction and on the third day of feed restriction. On the fourth day of feed restriction, the daily meal was not served and an intravenous glucose tolerance test was performed. During the 4 wk preceding the feed restriction, milk production and DMI were not affected by treatments. During the feed restriction, the vitamin supplement tended to decrease milk fat concentration and increase milk concentration of lactose. Plasma concentrations of homocysteine, Ile, Leu, Val, and branched-chain AA increased in VIT cows during the restriction but not in CON cows. During the glucose tolerance test, insulin peak height was lower and insulin incremental positive area under the curve tended to be lower for VIT than for CON [83 (95% confidence interval, CI: 64-108) vs. 123 (95% CI: 84-180) mu g.180 min/L, respectively]. Free fatty acid nadir was reached earlier for VIT than for CON [34 (95% CI: 26-43) vs. 46 (95% CI: 31-57) min, respectively]. Glucose area under the curve, clearance rate and peak height, insulin time to reach the peak and clearance rate, and free fatty acid nadir did not differ between VIT and CON. The reduction in insulin release during a glucose tolerance test without changes in glucose clearance rate or area under the curve suggests that the vitamin supplement improved insulin sensitivity in feed-restricted lactating dairy cows.

About 1-Phenylurea, If you have any questions, you can contact Girard, CL; Vanacker, N; Beaudet, V; Duplessis, M; Lacasse, P or concate me.. HPLC of Formula: C7H8N2O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2020 ORG BIOMOL CHEM published article about DIORGANYL DISELENIDES SYNTHESIS; C-H ACTIVATION; ELECTROPHILIC CYCLIZATION; IRON(III) CHLORIDE; BETA-PHENYLETHYLAMINES; CATALYZED ANNULATION; TANDEM CYCLIZATION; BOND FORMATION; DERIVATIVES; 2-ALKYNYLBENZALDEHYDES in [Sonawane, Amol D.; Sonawane, Rohini A.; Win, Khin Myat Noe; Ninomiya, Masayuki; Koketsu, Mamoru] Gifu Univ, Dept Chem & Biomol Sci, Fac Engn, Gifu 5011193, Japan in 2020, Cited 58. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6. Safety of 2-Aminobenzamide

An efficient, metal free and environment friendly synthesis of isoquinoline-fused benzimidazole has been developed via in situ air oxidation. Also, syntheses of isoquinoline-fused quinazolinone heteroacenes were successfully achieved. The synthesized isoquinoline-fused benzimidazole and isoquinoline-fused quinazolinone derivatives showed lambda(max), F-max and phi(f) values in the ranges 356-394 nm, 403-444 nm and 0.063-0.471, respectively, in CHCl3.

About 2-Aminobenzamide, If you have any questions, you can contact Sonawane, AD; Sonawane, RA; Win, KMN; Ninomiya, M; Koketsu, M or concate me.. Name: 2-Aminobenzamide

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

COA of Formula: C7H8N2O. Authors Wang, CC; Qu, YL; Liu, XH; Ma, ZW; Yang, B; Liu, ZJ; Chen, XP; Chen, YJ in AMER CHEMICAL SOC published article about in [Wang, Chuan-Chuan; Ma, Zhi-Wei; Liu, Zhi-Jing; Chen, Xiao-Pei] Henan Univ Anim Husb & Econ, Fac Sci, Zhengzhou 450044, Henan, Peoples R China; [Wang, Chuan-Chuan; Yang, Bo] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Henan, Peoples R China; [Qu, Ya-Li; Liu, Xue-Hua] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China; [Chen, Ya-Jing] Zhengzhou Univ, Minist Educ China, Sch Pharmaceut Sci, Key Lab Adv Drug Preparat Technol, Zhengzhou 450001, Henan, Peoples R China; [Chen, Ya-Jing] Zhengzhou Univ, Coinnovat Ctr Henan Prov New Drug R&D & Preclin S, Zhengzhou 450001, Henan, Peoples R China in 2021.0, Cited 57.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

The convenient preparation of N2-unprotected five-membered cyclic guanidines was achieved through a cascade [3 + 2] cycloaddition between organo-cyanamides and alpha-haloamides under mild conditions in good to excellent yields (up to 99%). The corresponding cyclic guanidines could be easily transformed into hydantoins via hydrolysis.

About 1-Phenylurea, If you have any questions, you can contact Wang, CC; Qu, YL; Liu, XH; Ma, ZW; Yang, B; Liu, ZJ; Chen, XP; Chen, YJ or concate me.. Computed Properties of C7H8N2O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Formula: C7H8N2O. Recently I am researching about NANOFIBERS; ARCHITECTURE; TRANSITION; NANOTUBES; GELATORS; NETWORKS; DESIGN; WATER, Saw an article supported by the Indonesia Endowment Fund for Education (LPDP)Ministry of Research and Technology of the Republic of Indonesia (RISTEK); Australian Research CouncilAustralian Research Council [DP180100845]; National Health and Medical Research CouncilNational Health and Medical Research Council of Australia [1106751]. Published in NATURE RESEARCH in BERLIN ,Authors: Aldilla, VR; Chen, RX; Martin, AD; Marjo, CE; Rich, AM; Black, DS; Thordarson, P; Kumar, N. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

In this study, we describe the synthesis and molecular properties of anthranilamide-based short peptides which were synthesised via ring opening of isatoic anhydride in excellent yields. These short peptides were incorporated as low molecular weight gelators (LMWG), bola amphiphile, and C-3-symmetric molecules to form hydrogels in low concentrations (0.07-0.30% (w/v)). The critical gel concentration (CGC), viscoelastic properties, secondary structure, and fibre morphology of these short peptides were influenced by the aromaticity of the capping group or by the presence of electronegative substituent (namely fluoro) and hydrophobic substituent (such as methyl) in the short peptides. In addition, the hydrogels showed antibacterial activity against S. aureus 38 and moderate toxicity against HEK cells in vitro.

Formula: C7H8N2O. About 2-Aminobenzamide, If you have any questions, you can contact Aldilla, VR; Chen, RX; Martin, AD; Marjo, CE; Rich, AM; Black, DS; Thordarson, P; Kumar, N or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about ACID-CATALYZED TRANSAMIDATION; N-SUBSTITUTED FORMAMIDES; CARBON-DIOXIDE; EFFICIENT SYNTHESIS; AMINES; DERIVATIVES; CARBOXAMIDES; METHANOL; OXIDATION; CO2, Saw an article supported by the Ministry of Science and Technology, TaiwanMinistry of Science and Technology, Taiwan [MOST 108-2113-M-005-019-]; National Chung Hsing University. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Huang, HY; Lin, XY; Yen, SY; Liang, CF. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide. Safety of 2-Aminobenzamide

N-Formamide synthesis usingN-formyl imide with primary and secondary amines with catalytic amounts ofp-toluenesulfonic acid monohydrate (TsOH center dot H2O) is described. This reaction is performed in water without the use of surfactants. Moreover,N-formyl imide is efficiently synthesized using acylamidines with TsOH center dot H2O in water. In addition,N-formyl imide was successfully used as a carbonyl source in the synthesis of benzimidazole and quinazolinone derivatives. Notable features ofN-formylation of amines by usingN-formyl imide include operational simplicity, oxidant- and metal-free conditions, structurally diverse products, and easy applicability to gram-scale operation.

About 2-Aminobenzamide, If you have any questions, you can contact Huang, HY; Lin, XY; Yen, SY; Liang, CF or concate me.. Application In Synthesis of 2-Aminobenzamide

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 88-68-6. Recently I am researching about C/EBP-ALPHA; INHIBITORS; CYTOTOXICITY; CANCER, Saw an article supported by the Singapore Ministry of Health’s National Medical Research Council under its Singapore Translational Research (STaR) Investigator AwardMinistry of Health-SingaporeNational Medical Research Council, Singapore; National Research Foundation SingaporeNational Research Foundation, Singapore; Singapore Ministry of Education under its Research Centres of Excellence initiativeMinistry of Education, Singapore; Cancer Science Institute of Singapore; National Institution of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [P01 CA66996, R21CA178301, R01CA169259]; American Cancer SocietyAmerican Cancer Society [RSG-13-047]; Harvard Stem Cell Institute Blood Program [DP-0110-12-00]; CSIR-HRDGCouncil of Scientific & Industrial Research (CSIR) – India [13(8906-A)/2017-pool]; CSIR, New DelhiCouncil of Scientific & Industrial Research (CSIR) – India [CSC0301]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Radhakrishnan, S; Syed, R; Takei, H; Kobayashi, IS; Nakamura, E; Sultana, F; Kamal, A; Tenen, DG; Kobayashi, SS. The CAS is 88-68-6. Through research, I have a further understanding and discovery of 2-Aminobenzamide

The tumor suppressor transcription factor CCAAT enhancer-binding protein alpha (C/EBP alpha) expression is down-regulated in myeloid leukemias and enhancement of C/EBP alpha expression induces granulocytic differentiation in leukemic cells. Previously we reported that Styryl quinazolinones induce myeloid differentiation in HL-60 cells by upregulating C/EBP alpha expression. To identify more potent molecule that can induce leukemic cell differentiation we synthesized and evaluated new series of styryl quinazolinones, ethynyl styryl quinazolinones, styryl quinolinones and thienopyrimidinones. Thienopyrimidinones were found toxic and styryl quinolinones were found inactive. Ethynyl styryl quinazolinone 39 and styryl quinazolinone 5 were found active on par with the earlier reported analogues 1 and 2 suggesting that the 5-nitro furan-2-yl styryl quinazolinones find a real promise in leukemic cell differentiation. The improved potency of 5 suggested that further modifications in the 5-nitro furan-2-yl styryl quinazolinones can be at the phenyl substitution at the 3-position of the quinazolinone ring apart from the 5-position of the heteroaryl ring.

Recommanded Product: 88-68-6. About 2-Aminobenzamide, If you have any questions, you can contact Radhakrishnan, S; Syed, R; Takei, H; Kobayashi, IS; Nakamura, E; Sultana, F; Kamal, A; Tenen, DG; Kobayashi, SS or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article A Route to Highly Functionalized Stereospecific trans -Aminated Aurones from 3-Bromoflavones with Aniline and N -Phenylurea via a Domino Aza-Michael Ring Opening and Cyclization Reactions WOS:000458836800017 published article about MEDIATED SYNTHESIS; INHIBITORS; FLAVONES; 6-ENDO-DIG; CLOSURE in [Parveen, Iram; Ahmed, Naseem] Indian Inst Technol Roorkee, Dept Chem, Roorkee 247667, Uttar Pradesh, India in 2019.0, Cited 36.0. Formula: C7H8N2O. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

A facile cascade reaction is reported via aza-Michael addition, ring opening, and cyclization between 3-bromoflavone and aniline derivatives or N -phenylurea in the presence of KO t -Bu and CuI in DMF under mild reaction conditions. Products were obtained as stereospecific trans -aminated aurones in good to excellent yields (61-83%). Our protocol is operationally successful with ease, avoids the requirement of additives and ligands, and offers broad substrate scope.

Formula: C7H8N2O. About 1-Phenylurea, If you have any questions, you can contact Parveen, I; Ahmed, N or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem