Heterocyclic Building Blocks-Thiomorpholine

An article An unexpected reaction of aryldiazonium tetrafluoroborates, sodium metabisulfite, and thiourea under photoinduced conditions WOS:000469257000016 published article about QUINOLINE N-OXIDES; H BOND FUNCTIONALIZATION; SULFUR-DIOXIDE; CATALYZED SYNTHESIS; SULFONYL HYDRAZIDES; 1,3-DIPOLAR CYCLOADDITION; STEREOSELECTIVE-SYNTHESIS; POTASSIUM METABISULFITE; 3-COMPONENT SYNTHESIS; DIARYLIODONIUM SALTS in [Gong, Xinxing; Wu, Jie; Ye, Shengqing] Taizhou Univ, Inst Adv Studies, 1139 Shifu Ave, Taizhou 318000, Peoples R China; [Gong, Xinxing; Wu, Jie] Fudan Univ, Dept Chem, 2005 Songhu Rd, Shanghai 200438, Peoples R China; [Li, Xiaofang; Xie, Wenlin] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China in 2019.0, Cited 131.0. Category: thiomorpholine. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

A photoinduced synthesis of S-aryl thiosulfonates through a three-component reaction of aryldiazonium tetrafluoroborates, sodium metabisulfite, and thiourea is achieved. The reaction scope generality with a range of aryldiazonium tetrafluoroborates is demonstrated. In this transformation, a radical coupling pathway is proposed with the insertion of sulfur dioxide in the presence of a photocatalyst under visible light irradiation. The organic sulfur motifs in S-aryl thiosulfonates originate from the convenient, cheap, and easily available thiourea and sodium metabisulfite.

About 1-Phenylurea, If you have any questions, you can contact Gong, XX; Li, XF; Xie, WL; Wu, J; Ye, SQ or concate me.. Category: thiomorpholine

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Application In Synthesis of Anthrone. Pencikova, K; Ciganek, M; Neca, J; Illes, P; Dvorak, Z; Vondracek, J; Machala, M in [Pencikova, Katerina; Ciganek, Miroslav; Neca, Jiri; Machala, Miroslav] Vet Res Inst, Dept Chem & Toxicol, Hudcova 70, Brno 62100, Czech Republic; [Illes, Peter; Dvorak, Zdenek] Palacky Univ, Fac Sci, Dept Cell Biol & Genet, Slechtitelu 27, Olomouc 78371, Czech Republic; [Vondracek, Jan] Czech Acad Sci, Inst Biophys, Dept Cytokinet, Kralovopolska 135, Brno 61265, Czech Republic published Modulation of endocrine nuclear receptor activities by polyaromatic compounds present in fractionated extracts of diesel exhaust particles in 2019, Cited 65. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

Organic pollutants associated with diesel exhaust particles (DEP), such as polycyclic aromatic hydrocarbons (PAHs) and their derivatives, may negatively impact human health. However, a comprehensive overview of their effects on endocrine nuclear receptor activities is still missing. Here, we evaluated the effects of extracts and chromatographic fractions (fractionated according to increasing polarity) of two standard reference materials derived from distinct types of diesel engines (SRM 2975, SRM 1650b), on activation of androgen receptor (AR), estrogen receptor alpha (ER alpha), peroxisome proliferator-activated receptor gamma (PPAR gamma), glucocorticoid receptor (GR) and thyroid receptor alpha (TR alpha), using human cell-based reporter gene assays. Neither DEP standard modulated AR or GR activities. Crude extracts and fractions of SRM 1650b and SRM 2975 suppressed ER alpha-mediated activity in the ER-CALUX (TM) assay; however, this effect could be partly linked to their cytotoxicity in this cell line. We observed that only SRM 2975 extract and its fractions were partial PPAR gamma inducers, while SRM 1650b extract was not active towards this receptor. Importantly, we found that both extracts and polar fractions of SRM activated TR alpha and significantly potentiated the activity of endogenous TR alpha ligand, triiodothyronine. Based on a detailed chemical analysis of both extracts and their polar fractions, we identified several oxygenated PAH derivatives, that were present at relatively high levels in the analyzed DEP standards, including 3-nitrobenzanthrone (3-NBA), anthracene-9,10-dione, phenanthrene-9,10-dione. 9H-fluoren-9-one or benzo[a] anthracene-7,12-dione, to activate TR alpha activity. Nevertheless, these compounds provided only a minor contribution to the overall TR alpha activity identified in polar fractions. This suggests that yet unidentified polar polyaromatic compounds associated with DEP may, apart from their known impact on the aryl hydrocarbon receptor or steroid signaling, deregulate activities of additional nuclear receptors, in particular of TR alpha. This illustrates the need to better characterize endocrine disrupting activities of DEP. (C) 2019 Elsevier B.V. All rights reserved.

About Anthrone, If you have any questions, you can contact Pencikova, K; Ciganek, M; Neca, J; Illes, P; Dvorak, Z; Vondracek, J; Machala, M or concate me.. Application In Synthesis of Anthrone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about HYDROGEN-ATOM TRANSFER; C-H BONDS; MOLECULAR-OXYGEN; CATALYTIC-SYSTEM; FERRIC NITRATE; PHTHALIMIDE; HYDROXYPHTHALIMIDE; REACTIVITY; OXYL; ALKYLBENZENES, Saw an article supported by the Zhejiang Provincial Natural Science FoundationNatural Science Foundation of Zhejiang Province [LY21H300003]; Department of Education of Zhejiang Province [Y201942551]; Hangzhou Medical College [00004F1RCYJ1804]. Safety of Benzophenone. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Wang, J; Zhang, C; Ye, XQ; Du, WT; Zeng, SX; Xu, JH; Yin, H. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone

An efficient and practical benzylic aerobic oxidation catalyzed by cheap and simple N-hydroxyimide organocatalyst has been achieved with high yields and broad substrate scope. The organocatalyst used can be recycled and reused by simple workup and only minute amount (1 mol% in most cases) of simple iron salt is used as promoter. Phenyl substrates with mild and strong electron-withdrawing group could also be oxygenated in high yields as well as other benzylic methylenes. Influence of substituents, gram-scale application, catalysts decay and general mechanism of this methodology has also been discussed.

About Benzophenone, If you have any questions, you can contact Wang, J; Zhang, C; Ye, XQ; Du, WT; Zeng, SX; Xu, JH; Yin, H or concate me.. Safety of Benzophenone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Biodegradation of anthracene and different PAHs by a yellow laccase from Leucoagaricus gongylophorus WOS:000464851100028 published article about POLYCYCLIC AROMATIC-HYDROCARBONS; TRAMETES-VERSICOLOR; OXIDATION; DEGRADATION; PURIFICATION; ENZYMES in [Leme Ike, Priscila Tomie; Ferreira Souza, Dulce Helena] Univ Fed Sao Carlos, Ctr Ciencias Exatas & Tecnol, Dept Quim, Rodovia Washington Luis,Km 235, BR-13565905 Sao Carlos, SP, Brazil; [Leme Ike, Priscila Tomie] Inst Fed Parana, Rua Antonio Carlos Rodrigues 453, BR-87703539 Paranagua, PR, Brazil; [Birolli, Willian Garcia; dos Santos, Danilo Martins; Meleiro Porto, Andre Luiz] Univ Sao Paulo, Lab Quim Organ & Biocatalise, Inst Quim Sao Carlos, Av Joao Dagnone 1100,Ed Quim Ambiental, BR-13563120 Sao Carlos, SP, Brazil in 2019, Cited 42. Recommanded Product: 90-44-8. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Laccases produced by Leucoagaricus gongylophorus act in lignocellulose degradation and detoxification processes. Therefore, the use of L. gongylophorus laccase (Lac1Lg) was proposed in this work for degradation of anthracene and others polycyclic aromatic hydrocarbons without the use of mediators. Degradation reactions were performed in buffer aqueous solution with 10 ppm of anthracene and other PAHs, Tween-20 in 0.25% v/v and a laccase preparation of 50 U. The optimum condition (pH 6.0 and 30 degrees C) was determined by response surface methodology with an excellent coefficient of determination (R-2) of 0.97 and an adjusted coefficient of determination (R-adj(2)) of 0.93. In addition, the employment of the mediator ABTS decreased the anthracene biodegradation from 44 +/- 1% to 30 +/- 1%. This optimum pH of 6.0 suggests that the reaction occurs by a hydrogen atom transfer mechanism. Additionally, in 24 h Lac1Lg biodegraded 72 +/- 1% anthracene, 40 +/- 3% fluorene and 25 +/- 3% phenanthrene. The yellow laccase from L. gongylophorus biodegraded anthracene and produced anthrone and anthraquinone, which are interesting compounds for industrial applications. Moreover, this enzyme also biodegraded the PAHs phenanthrene and fluorene justifying the study of Lac1Lg for bioremediation of these compounds in the environment.

Recommanded Product: 90-44-8. About Anthrone, If you have any questions, you can contact Ike, PTL; Birolli, WG; dos Santos, DM; Porto, ALM; Souza, DHF or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Cross-kingdom interaction of Candida albicans and Actinomyces viscosus elevated cariogenic virulence WOS:000463128900013 published article about ROOT SURFACE CARIES; STREPTOCOCCUS-MUTANS; IN-SITU; ADHESION FORCES; BACTERIAL; DENTIN; ATTACHMENT; BIOFILMS; PATHOGENESIS; MICROFLORA in [Deng, Ling; Li, Wei; He, Yuanli; Wu, Juan; Ren, Biao] Sichuan Univ, State Key Lab Oral Dis, Chengdu 610041, Sichuan, Peoples R China; [Zou, Ling] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Dept Cariol & Endodont,State Key Lab Oral Dis, Chengdu 610041, Sichuan, Peoples R China in 2019, Cited 43. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8. Safety of Anthrone

Objective: How the interactions between Candida albicans and Actinomyces viscosus contributed to the root caries was not clear. This study aimed to investigate their cross-kingdom interactions on the biomass and the cariogenic virulence in dual-species biofilms. Design: Suspensions of C. albicans and A. viscosus were formed the mono and polymicrobial biofilms in vitro. Crystal violet assay, viable plate count, scanning electron microscopy and fluorescence in situ hybridization were used to analyze the biomass and biofilm structure. Glycolytic pH drop and the spectrophotometric method were used to evaluate the acid production and hydroxyapatite dissolution, respectively. The exopolysaccharide production was measured by the anthrone-sulfuric acid method, while the adhesion force was measured by atomic force microscopy. Results: The biomass and colony-forming units of mixed-species were significantly increased compared to that of the mono-species at 24 h, 48 h, 72 h. The structure of dual-species biofilm had more microcolonies and was much denser. The dual-species biofilms significantly decreased the pH value and damaged the hydroxyapatite compared with the mono-species biofilms at various time points, indicating the strong cariogenic virulence. Moreover, the dual-species biofilms significantly enhanced the exopolysaccharide production and adhesion force suggesting the increase of biofilm adhesion. Conclusions: Cross-kingdom interactions of C. albicans and A. viscosus significantly elevated the biomass and cariogenic virulence of dual-species biofilm.

Safety of Anthrone. About Anthrone, If you have any questions, you can contact Deng, L; Li, W; He, YL; Wu, J; Ren, B; Zou, L or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Quality Control of 2-Aminobenzamide. Authors Yang, L; Hou, HQ; Li, L; Wang, J; Zhou, SY; Wu, M; Ke, F in ROYAL SOC CHEMISTRY published article about in [Yang, Li; Li, Lan; Ke, Fang] Yibin Univ, Coll Chem & Chem Engn, Yibin, Sichuan, Peoples R China; [Hou, Huiqing; Wang, Jin; Zhou, Sunying; Wu, Mei; Ke, Fang] Fujian Med Univ, Fuzhou, Fujian, Peoples R China in 2021, Cited 64. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6

An efficient and practical electrochemically catalyzed transition metal-free process for the synthesis of substituted quinazolinones from simple and readily available o-aminobenzonitriles and aldehydes in water has been accomplished. I-2/base and water play an unprecedented and vital role in the reaction. By electrochemically catalysed hydrolysis of o-aminobenzonitriles, the synthesis of quinazolinones with benzaldehyde was first proposed. The synthetic utility of this method was demonstrated by gram-scale operation, as well as the preparation of bioactive N-(2,5-dichlorophenyl)-6-(2,2,2-trifluoroethoxy) pteridin-4-amine, which enables straightforward, practical and environmentally benign quinazolinone formation.

Quality Control of 2-Aminobenzamide. About 2-Aminobenzamide, If you have any questions, you can contact Yang, L; Hou, HQ; Li, L; Wang, J; Zhou, SY; Wu, M; Ke, F or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Al-Sehemi, AG; Irfan, A; Pannipara, M; Assiri, MA; Kalam, A in [Al-Sehemi, Abdullah G.; Irfan, Ahmad; Pannipara, Mehboobali; Assiri, Mohammed A.; Kalam, Abul] King Khalid Univ, Dept Chem, Fac Sci, POB 9004, Abha 61413, Saudi Arabia; [Al-Sehemi, Abdullah G.; Irfan, Ahmad; Pannipara, Mehboobali; Assiri, Mohammed A.; Kalam, Abul] King Khalid Univ, RCAMS, POB 9004, Abha 61413, Saudi Arabia published Anthracene Based AIE Active Probe for Colorimetric and Fluorimetric Detection of Cu2+ Ions in 2019, Cited 37. SDS of cas: 88-68-6. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.

A novel aggregation induced emission (AIE) active anthracene based dihydroquinazolinone derivative (probe 1) has been synthesized and characterized by means of spectroscopic methods. The photophysical properties of this probe have been investigated in solvents of different polarity display that fluorescence states are of intramolecular charge transfer (ICT) character. Probe 1 show clear AIE behavior in water/THF mixture on reaching water fraction 95%. The AIE behavior of probe 1 have been exploited for the detection of metal ions in aqueous solution which reveals high selectivity and sensitivity towards Cu2+ ions by colorimetrically and function as a chemosensor in a remarkable turn-off fluorescence manner. Further, the experimental results were investigated by computational means by optimizing the ground state geometries of probe 1 and probe 1-Cu complex using density functional theory (DFT) at B3LYP/6-31G** and B3LYP/6-31G**(LANL2DZ) levels of theory. Intra-molecular charge transfer was observed in probe 1 while ligand to metal charge transfer (LMCT) for probe 1-Cu complex.

SDS of cas: 88-68-6. About 2-Aminobenzamide, If you have any questions, you can contact Al-Sehemi, AG; Irfan, A; Pannipara, M; Assiri, MA; Kalam, A or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Product Details of 119-61-9. Authors Mohamed, MG; Tsai, MY; Wang, CF; Huang, CF; Danko, M; Dai, LZ; Chen, T; Kuo, SW in MDPI published article about in [Gamal Mohamed, Mohamed; Tsai, Mei-Yin; Kuo, Shiao-Wei] Natl Sun Yat Sen Univ, Ctr Crystal Res, Dept Mat & Optoelect Sci, Kaohsiung 80424, Taiwan; [Gamal Mohamed, Mohamed] Assiut Univ, Dept Chem, Fac Sci, Assiut 71516, Egypt; [Wang, Chih-Feng] Natl Taiwan Univ Sci & Technol, Grad Inst Appl Sci & Technol, Adv Membrane Mat Res Ctr, Taipei 10607, Taiwan; [Huang, Chih-Feng] Natl Chung Hsing Univ, i Ctr Adv Sci & Technol, Dept Chem Engn, Taichung 40227, Taiwan; [Danko, Martin] Slovak Acad Sci, Inst Polymer, Dept Synth & Characterizat Polymers, Dubravska Cesta 9, Bratislava 84541, Slovakia; [Dai, Lizong] Xiamen Univ, Coll Mat, Fujian Prov Key Lab Fire Retardant Mat, Xiamen 361005, Peoples R China; [Chen, Tao] Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Ningbo 315201, Peoples R China; [Kuo, Shiao-Wei] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 807, Taiwan in 2021.0, Cited 73.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

In this study, two different types of hybrid porous organic polymers (POPs), polyhedral oligomeric silsesquioxane tetraphenylpyrazine (POSS-TPP) and tetraphenylethene (POSS-TPE), were successfully synthesized through the Friedel-Crafts polymerization of tetraphenylpyrazine (TPP) and tetraphenylethene (TPE), respectively, with octavinylsilsesquioxane (OVS) as node building blocks, in the presence of anhydrous FeCl3 as a catalyst and 1,2-dichloroethane at 60 degrees C. Based on N-2 adsorption and thermogravimetric analyses, the resulting hybrid porous materials displayed high surface areas (270 m(2)/g for POSS-TPP and 741 m(2)/g for POSS-TPE) and outstanding thermal stabilities. Furthermore, as-prepared POSS-TPP exhibited a high carbon dioxide capacity (1.63 mmol/g at 298 K and 2.88 mmol/g at 273 K) with an excellent high adsorption capacity for iodine, reaching up to 363 mg/g, compared with the POSS-TPE (309 mg/g).

About Benzophenone, If you have any questions, you can contact Mohamed, MG; Tsai, MY; Wang, CF; Huang, CF; Danko, M; Dai, LZ; Chen, T; Kuo, SW or concate me.. Product Details of 119-61-9

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Green and efficient one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones and their anthelmintic studies WOS:000479868400001 published article about N-SULFONIC ACID; IONIC LIQUID; CATALYST; DERIVATIVES; PROLINE; FACILE in [Kharmawlong, George Kupar; Nongrum, Ridaphun; Rani, Urns World Star; Rahman, Noimur; Nongkhlaw, Rishanlang] North Eastern Hill Univ, Ctr Adv Studies, Dept Chem, Shillong 793022, Meghalaya, India; [Chhetri, Bhusan; Yadav, Arun Kumar] North Eastern Hill Univ, Dept Zool, Shillong, Meghalaya, India in 2019, Cited 41. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6. SDS of cas: 88-68-6

A facile and highly efficient one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives has been developed by the condensation of anthranilamide with aldehydes using sulfonic acid functionalized l-Proline@Fe3O4 nanoparticles as a catalyst. The advantages of this protocol are easy recovery and reusability of the catalyst besides simple work-up procedure and short reaction time. In addition, the anthelmintic activities of some selective compounds were investigated and it was found that 2-phenyl-2,3-dihydroquinazolin-4(1H)-one exhibited profound anthelmintic activity against two helminth models. [GRAPHICS]

SDS of cas: 88-68-6. About 2-Aminobenzamide, If you have any questions, you can contact Kharmawlong, GK; Nongrum, R; Chhetri, B; Rani, UWS; Rahman, N; Yadav, AK; Nongkhlaw, R or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article HPLC-DAD-Q-ToF-MS profiling of phenolic compounds from mango (Mangifera indica L.) seed kernel of different cultivars and maturation stages as a preliminary approach to determine functional and nutraceutical value WOS:000576952500027 published article about BIOACTIVE COMPOUNDS; ELLAGIC ACID; BY-PRODUCTS; ANTIOXIDANT; QUANTIFICATION; POLYPHENOLICS; GALLOTANNINS; QUALITY; HEALTH; FRUITS in [Alanon, M. E.] Univ Castilla La Mancha, Higher Tech Sch Agron Engn, Dept Analyt Chem & Food Technol, Ronda Calatrava 7, Ciudad Real 13071, Spain; [Alanon, M. E.; Pimentel-Moral, S.; Arraez-Roman, D.; Segura-Carretero, A.] Univ Granada, Fac Sci, Dept Analyt Chem, Campus Fuentenueva S-N, Granada 18071, Spain; [Alanon, M. E.; Pimentel-Moral, S.; Arraez-Roman, D.; Segura-Carretero, A.] PTS Granada, Res & Dev Funct Food Ctr CIDAF, Avda Conocimiento S-N, Granada 18016, Spain in 2021.0, Cited 41.0. Computed Properties of C13H10O. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

Mango seed kernel is a by-product which is usually discarded. However, it has been confirmed in this study that seed kernel exhibits more phenolic compounds with bioactive properties than edible fraction of mango. The influence of factors such as cultivar and maturation degree on the phenolic composition has been studied to evaluate nutraceutical value. The comprehensive analysis of phenolic composition by HPLC-DAD-Q-ToF-MS seed kernel from different cultivars (‘Keth’, ‘Kent’and ‘Osteen’) at five maturation stages was conducted. Results evidenced that `Keitt’ samples exhibited higher quantities of iriflophenone glucoside, maclurin C-glucoside, maclurin digalloyl glucoside, mangiferin, 5-galloyl quinic acid and trigalloyl glucose at the first three ripening stages. However, seed kernel from `Osteen’ variety showed higher amounts of hexa- and hepta-gallotannins whose concentrations diminished over the maturation course. Therefore, cultivar and maturation stage factors should be take into account due to their influence on the phenolic composition and subsequently on the nutraceutical value.

Computed Properties of C13H10O. About Benzophenone, If you have any questions, you can contact Alanon, ME; Pimentel-Moral, S; Arraez-Roman, D; Segura-Carretero, A or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem