Heterocyclic Building Blocks-Thiomorpholine

HPLC of Formula: C7H8N2O. Authors Heriyanto; Pahlevani, F; Sahajwalla, V in ELSEVIER SCI LTD published article about in [Heriyanto; Pahlevani, Farshid; Sahajwalla, Veena] UNSW, Sch Mat Sci & Engn, Ctr Sustainable Mat Res & Technol SMaRT, Sydney, NSW 2052, Australia in 2019.0, Cited 24.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

This study reports an innovative pathway for successfully synthesizing composite panels using various waste input. For this purpose, seven types of powder from waste or widely available filler i.e. Quartz off-cut, sand, waste seashell, dolomite, limestone aggregates, concrete waste and limestone dust were used. The study aims to assess the effectiveness and mechanical properties of the various waste powder in the production of powder-resin composites. The panels were then compared with the novel polymeric glass composite (PGC) in the previous study (Heriyanto et al., 2018). Following the same procedure in PGC, the filler was individually grounded to 64-108 mu m and chemically treated with amino silane coupling agent (CA). The powder filler (untreated or treated) is then mixed with the resin binder with a ratio of 80/20 respectively, followed by hot pressing the mixture at the pressure of 550 bar at 65 degrees C for 1 h. The final composite slab is then further cut for mechanical testing. It was found in the study that when CA was not added, surface roughness of the powder particles affected the flexural strength of the final panel significantly. High surface roughness particles such as in Quartz, sand and seashell adhere effectively with the resin binder which led to higher strength. On the contrary, other factors like smooth particle morphology in glass, dolomite and limestone as well as porous structure in concrete and clump of very fine powder in limestone dust degrade the strength of the final panels. With CA addition, adhesion between resin and powder filler were improved significantly. Flexural strength after the CA treatment was found to be much affected by particle characteristics. Silica-based panels i.e. quartz, sand and glass which consist of high strength and hardness of silica particles perform better compared to that of calcium carbonate-based panels. Compression strength, toughness, stiffness, scratch resistance, density and water absorption were also reported in this study. The properties of all the treated panels are found to be comparable, or if not, much better than natural stones. These new approaches of using waste filler in powder – resin based composites can be a new alternative to produce green materials that deliver economic and environmental benefits. (C) 2019 Elsevier Ltd. All rights reserved.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Martini, G; Cardone, C; Vitiello, PP; Belli, V; Napolitano, S; Troiani, T; Ciardiello, D; Della Corte, CM; Morgillo, F; Matrone, N; Sforza, V; Papaccio, G; Desiderio, V; Paul, MC; Moreno-Viedma, V; Normanno, N; Rachiglio, AM; Tirino, V; Maiello, E; Latiano, TP; Rizzi, D; Signoriello, G; Sibilia, M; Ciardiello, F; Martinelli, E in [Martini, Giulia; Cardone, Claudia; Vitiello, Pietro Paolo; Belli, Valentina; Napolitano, Stefania; Troiani, Teresa; Ciardiello, Davide; Della Corte, Carminia Maria; Morgillo, Floriana; Matrone, Nunzia; Ciardiello, Fortunato; Martinelli, Erika] Univ Campania L Vanvitelli, Med Oncol, Dept Precis Med, Via Pansini 5, I-80131 Naples, Italy; [Sforza, Vincenzo] Fdn Pascale, IRCCS, Ist Nazl Tumori, Dept Clin Expt Thorac Oncol, Naples, Italy; [Papaccio, Gianpaolo; Desiderio, Vincenzo; Tirino, Virginia] Univ Campania Luigi Vanvitelli Napoli, Dept Expt Med, Naples, Italy; [Paul, Mariel C.; Moreno-Viedma, Veronica; Sibilia, Maria] Med Univ Vienna, Comprehens Canc Ctr, Dept Med 1, Inst Canc Res, Borschkegasse 8a, Vienna, Austria; [Normanno, Nicola; Rachiglio, Anna Maria] Fdn Pascale, IRCCS, Ist Nazl Tumori, Cell Biol & Biotherapy Unit, Naples, Italy; [Maiello, Evaristo; Latiano, Tiziana Pia; Rizzi, Daniele] Hosp Casa Sollievo Della Sofferenza San Giovanni, Med Oncol, San Giovanni Rotondo, Italy; [Signoriello, Giuseppe] Univ Campania L Vanvitelli, Biostat, Dipartimento Salute Mentale & Fis & Med Prevent, Naples, Italy published EPHA2 Is a Predictive Biomarker of Resistance and a Potential Therapeutic Target for Improving Antiepidermal Growth Factor Receptor Therapy in Colorectal Cancer in 2019.0, Cited 24.0. SDS of cas: 64-10-8. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8.

The EPHA2 tyrosine kinase receptor is implicated in tumor progression and targeted therapies resistance. We evaluated EPHA2 as a potential resistance marker to the antiepidermal growth factor receptor (EGFR) monoclonal antibody cetuximab in colorectal cancer. We studied activation of EPHA2 in a panel of human colorectal cancer cell lines sensitive or resistant to anti-EGFR drugs. The in vitro and in vivo effects of ALW-II-41-27 (an EPHA2 inhibitor) and/or cetuximab treatment were tested. Fonnalin-fixed paraffin-embedded tumor specimens from 82 RAS wild-type (WV) metastatic colorectal cancer patients treated with FOLFIRI + cetuximab as first-line therapy in the CAPRI-COIM trial were assessed for EPHA2 expression by immunohistochemistry and correlated with treatment efficacy. EPHA2 was differentially activated in colorectal cancer cell lines. Combined treatment with ALW-II-41-27 plus cetuximab reverted primary and acquired resistance to cetuximab, causing cell growth inhibition, inducing apoptosis and cell-cycle G1-G2 arrest. In tumor xenograft models, upon progression to cetuximab, ALW-II-41-27 addition significantly inhibited tumor growth. EPHA2 protein expression was detected in 55 of 82 tumor samples, frequently expressed in less-differentiated and left-sided tumors. High levels of EPHA2 significantly correlated with worse progression-free survival [8.6 months; confidence interval (CI) 95%, 6.4-10.8; vs. 12.3 months; CI 95%, 10.4-14,2; P = 0.03] and with increased progression rate (29% vs. 9%, P = 0.02). A specific EPHA2 inhibitor reverts in vitro and in vivo primary and acquired resistance to anti-ECFR therapy. EPHA2 levels are significantly associated with worse outcome in patients treated with FOLFIRI + cetuximab. These results highlight EPHA2 as a potential therapeutic target in metastatic colorectal cancer.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Using an electronic nose and volatilome analysis to differentiate sparkling wines obtained under different conditions of temperature, ageing time and yeast formats WOS:000569687200006 published article about 2ND FERMENTATION; BOTTLE; QUALITY; AROMA; BASE; LEES in [Martinez-Garcia, Rafael; Moreno, Juan; Peinado, Rafael A.] Univ Cordoba, Dept Agr Chem, Agrifood Campus Int Excellence CeiA3, Marie Curie C3 Bldg,Ctra N-4-A,Km 396, Cordoba 14014, Spain; [Carlos Mauricio, Juan; Garcia-Martinez, Teresa] Univ Cordoba, Dept Microbiol, Agrifood Campus Int Excellence CeiA3, Severo Ochoa C6 Bldg,Ctra N-4-A,Kmm 396, Cordoba 14014, Spain; [Bellincontro, Andrea; Centioni, Luna] Univ Tuscia, Dept Innovat Biol, Agrofood & Forest Syst Postharvest Lab, DIBAF, Via San Camillo de Lellis Snc, I-01100 Viterbo, Italy; [Puig-Pujol, Anna] Inst Recerca & Tecnol Agroalimentaries, Inst Catala Vinya & Vi, Placa Agora 2, Barcelona 08720, Spain in 2021.0, Cited 39.0. Product Details of 119-61-9. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

Effect of yeast inoculation format (F), temperature (T), and on lees ageing time (t) factors were evaluated on the composition of sparkling wines by a quantitative fingerprint obtained from volatile metabolites and the response of an electronic nose (E-nose). Wines elaborated according the traditional method at 10 and 14 degrees C, free cells and yeast biocapsules formats were monitored at 15 and 24 months of ageing time. Sixty-six volatiles identified and quantified in the eight sampling lots were subjected to a pattern recognition technique. A dual criterion based on univariate (ANOVA) and multivariate analysis (PLS-DA) through the variable importance projection (VIP) values, allowed to identify ten volatiles as potential markers for T factor, eleven fort and twelve for F factors. The discriminant models based on E-nose dataset enable a 100% correct classification of samples, in relation with t and F factors and the 83% for T factor.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 119-61-9. Authors Dmitrienko, A; Pilkington, M; Nikonov, GI in WILEY-V C H VERLAG GMBH published article about in [Dmitrienko, Anton; Pilkington, Melanie; Nikonov, Georgii I.] Brock Univ, Dept Chem, 1812 Sir Isaac Brock Way, St Catharines, ON L2S 3A1, Canada in 2021.0, Cited 22.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

The Al-I compound NacNacAl (1, NacNac = [ArNC(Me)CHC(Me)NAr](-), Ar = 2,6-iPr(2)C(6)H(3)) serves as a template for the chemoselective coupling between carbonyls (benzophenone, fenchone, isophorone, p-tolyl benzoate, N,N-dimethylbenzamide, (1-phenylethylidene)aniline) and pyridine. With the CH-acidic ketone (1R)-(+) camphor, the reaction affords a hydrido alkoxide compound of Al, formed as the result of enolization, whereas an enolizable imine, (1-phenylethylidene)aniline, and the bulky ketone isophorone, still chemoselectively couple with pyridine. In contrast, reaction with the ester p-tolyl benzoate results in cleavage of the ester bond together with replacement of the alkoxy group by a hydrogen atom of the pyridine moiety. This study demonstrates that for carbonyl substrates featuring phenyl substituents, the reaction proceeds via intermediate formation of eta(2)(C,X)-coordinated (X = O, N) carbonyl adducts, whereas the reaction of 1 with (R)-(-)-fenchone in the absence of pyridine leads to CH activation in the pendant isopropyl group of the Ar substituent of the NacNac ligand.

Welcome to talk about 119-61-9, If you have any questions, you can contact Dmitrienko, A; Pilkington, M; Nikonov, GI or send Email.. Recommanded Product: 119-61-9

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recently I am researching about ANDROGEN RECEPTOR; HISTONE H3; COACTIVATOR; CARM1; METHYLATION; DISCOVERY; TRANSCRIPTION; EXPRESSION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91853126]; Natural Science Foundation of China for Innovation Research GroupNational Natural Science Foundation of China (NSFC) [81821005]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA12020371, XDA12020365]; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program of China [2018ZX09711002-004-002, 2018ZX09711002-004-014]; Collaborative Innovation Cluster Project of Shanghai Municipal Commission of Health and Family Planning [2019CXJQ02]; Shanghai Talent Development Founds [201663]. Application In Synthesis of 1-Phenylurea. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Guo, ZH; Zhang, ZQ; Yang, H; Cao, DY; Xu, XW; Zheng, XN; Chen, DQ; Wang, Q; Li, YL; Li, J; Du, ZY; Wang, X; Chen, L; Ding, J; Shen, JK; Geng, MY; Huang, X; Xiong, B. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea

PRMT4 is a type I protein arginine methyltransferase and plays important roles in various cellular processes. Overexpression of PRMT4 has been found to be involved in several types of cancers. Selective and in vivo effective PRMT4 inhibitors are needed for demonstrating PRMT4 as a promising therapeutic target. On the basis of compound 6, a weak dual PRMT4/6 inhibitor, we constructed a tetrahydroisoquinoline scaffold through a cut-and-sew scaffold hopping strategy. The subsequent SAR optimization efforts employed structure-based approach led to the identification of a novel PRMT4 inhibitor 49. Compound 49 exhibited prominently high potency and selectivity, moderate pharmacokinetic profiles, and good antitumor efficacy in acute myeloid leukemia xenograft model via oral administration, thus demonstrating this compound as a useful pharmacological tool for further target validation and drug development in cancer therapy.

Welcome to talk about 64-10-8, If you have any questions, you can contact Guo, ZH; Zhang, ZQ; Yang, H; Cao, DY; Xu, XW; Zheng, XN; Chen, DQ; Wang, Q; Li, YL; Li, J; Du, ZY; Wang, X; Chen, L; Ding, J; Shen, JK; Geng, MY; Huang, X; Xiong, B or send Email.. Application In Synthesis of 1-Phenylurea

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

COA of Formula: C13H10O. Authors Barretta, C; Oreski, G; Feldbacher, S; Resch-Fauster, K; Pantani, R in MDPI published article about in [Barretta, Chiara; Oreski, Gernot; Feldbacher, Sonja] Polymer Competence Ctr Leoben GmbH, Roseggerstr 12, A-8700 Leoben, Austria; [Resch-Fauster, Katharina] Univ Leoben, Inst Mat Sci & Testing Plast, Otto Glockl Str 8, A-8700 Leoben, Austria; [Pantani, Roberto] Univ Salerno, Dept Ind Engn, Via Giovanni Paolo II, I-84084 Fisciano, Italy in 2021.0, Cited 43.0. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

The main focus of this work is to investigate the degradation behavior of two newly developed encapsulants for photovoltaic applications (thermoplastic polyolefin (TPO) and polyolefin elastomer (POE)), compared to the most widely used Ethylene Vinyl Acetate (EVA) upon exposure to two different artificial ageing tests (with and without ultraviolet (UV) irradiation). Additive composition, optical and thermal properties and chemical structure (investigated by means of Thermal Desorption Gas Chromatography coupled to Mass Spectrometry, UV-Visible-Near Infrared spectroscopy, Differential Scanning Calorimetry, Thermogravimetric Analysis and Fourier Transform-Infrared spectroscopy, respectively) of the analyzed polymers were monitored throughout the exposure to artificial ageing tests. Relevant signs of photo-oxidation were detectable for TPO after the UV test, as well as a depletion of material’s stabilizers. Signs of degradation for EVA and POE were detected when the UV dose applied was equal to 200 kW h m(-2). A novel approach is presented to derive information of oxidation induction time/dose from thermogravimetric measurements that correlate well with results obtained by using oxidation indices.

COA of Formula: C13H10O. Bye, fridends, I hope you can learn more about C13H10O, If you have any questions, you can browse other blog as well. See you lster.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Preparation, surface activities, and aggregation behaviors of N-acyl oligopeptide surfactants based on glycylglycine and glycylglycylglycine WOS:000663628400002 published article about AMINO-ACID SURFACTANTS; PEPTIDE AMPHIPHILE; SODIUM; STABILITY; MICELLIZATION; FLUORESCENCE; ASSEMBLIES; GLYCINE; BOND in [Zhang, Jieying; Li, Qiannan; Wang, Shengnan; Zhang, Guiju; He, Shan; Liu, Changyao; Wang, Ce; Xu, Baocai] Beijing Technol & Business Univ, Sch Light Ind, 11 Fucheng Rd, Beijing 100048, Peoples R China in 2021.0, Cited 36.0. Name: Benzophenone. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

With the growing concern about safety and environmental issues, amino acid-based surfactants have great potential as sustainable and eco-friendly substances. In the present study, six N-acyl oligopeptide surfactants were synthesized using fatty acid methyl esters (i.e., methyl caprate, methyl laurate, and methyl myristate) and glycyl oligopeptides (i.e., glycylglycine and glycylglycylglycine). Surface active properties and aggregation behaviors of these surfactants were investigated using surface tension, fluorescence probe, dynamic light scattering, and microscopy measurements. The adsorption at the air-water interface and aggregation in the aqueous solution depend on the structure of both hydrophilic head-groups and hydrophobic tails. Spherical vesicles were observed in the aqueous solutions of glycylglycine derivatives, whereas short tubular aggregates were found in that of corresponding glycylglycylglycine products. Intermolecular hydrogen-bonding interaction between the amide head-groups might be responsible for the different self-assembly behavior and microstructure of N-acyl oligopeptide surfactants in the aqueous solution.

Name: Benzophenone. Bye, fridends, I hope you can learn more about C13H10O, If you have any questions, you can browse other blog as well. See you lster.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

COA of Formula: C13H10O. Recently I am researching about BIOACTIVE COMPOUNDS; ELLAGIC ACID; BY-PRODUCTS; ANTIOXIDANT; QUANTIFICATION; POLYPHENOLICS; GALLOTANNINS; QUALITY; HEALTH; FRUITS, Saw an article supported by the Junta de Comunidades de Castilla-La ManchaJunta de Comunidades de Castilla-La Mancha [SBPLY/17/180501/000509]; Ibero-American Program of Science and Technology for Development, CYTED [118RT0543]; project of Consejeria de Economia, Conocimiento, Empresas y Univerisdad from Junta de AndaluciaJunta de Andalucia [P18TP-3589]; FEDEREuropean Commission. Published in ELSEVIER SCI LTD in OXFORD ,Authors: Alanon, ME; Pimentel-Moral, S; Arraez-Roman, D; Segura-Carretero, A. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone

Mango seed kernel is a by-product which is usually discarded. However, it has been confirmed in this study that seed kernel exhibits more phenolic compounds with bioactive properties than edible fraction of mango. The influence of factors such as cultivar and maturation degree on the phenolic composition has been studied to evaluate nutraceutical value. The comprehensive analysis of phenolic composition by HPLC-DAD-Q-ToF-MS seed kernel from different cultivars (‘Keth’, ‘Kent’and ‘Osteen’) at five maturation stages was conducted. Results evidenced that `Keitt’ samples exhibited higher quantities of iriflophenone glucoside, maclurin C-glucoside, maclurin digalloyl glucoside, mangiferin, 5-galloyl quinic acid and trigalloyl glucose at the first three ripening stages. However, seed kernel from `Osteen’ variety showed higher amounts of hexa- and hepta-gallotannins whose concentrations diminished over the maturation course. Therefore, cultivar and maturation stage factors should be take into account due to their influence on the phenolic composition and subsequently on the nutraceutical value.

COA of Formula: C13H10O. Welcome to talk about 119-61-9, If you have any questions, you can contact Alanon, ME; Pimentel-Moral, S; Arraez-Roman, D; Segura-Carretero, A or send Email.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 1-Phenylurea. Authors Fernandez-Lobato, L; Lopez-Sanchez, Y; Blejman, G; Jurado, F; Moyano-Fuentes, J; Vera, D in ELSEVIER SCI LTD published article about in [Fernandez-Lobato, L.; Jurado, F.; Vera, D.] Univ Jaen, Escuela Politecn Super, Dept Elect Engn, Linares 23700, Spain; [Lopez-Sanchez, Y.] Univ Jaen, Dept Econ, Lab Anal & Innovat Tourism LAInnTUR, Jaen, Spain; [Blejman, G.] Circular Carbon GmbH, Madrid, Spain; [Moyano-Fuentes, J.] Univ Jaen, Escuela Politecn Super, Dept Business Org Mkt & Sociol, Linares 23700, Spain in 2021.0, Cited 57.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

Spain is the first olive oil producer worldwide (representing around 45%), with more than 80% of its agricultural area dedicated to this crop. The goal of this study is to assess the environmental impact of the Spanish virgin olive oil production, attending to the farming and industrial phases. A Life Cycle Assessment (LCA) is conducted for 5 harvests in approximately 4.000 ha of olive grove in Jaen, the largest producer region of Spain. The type of farming is the most representative in Spain: conventional (non-organic), with a medium-low slope, extensive (100-150 trees per ha) and around 60% dryland orchards. The industrial phase is based on 2-phase extraction process and olive pomace valorization. The functional unit (FU) chosen for the comparative analysis is 1 kg of unpacked virgin olive oil under a perspective from cradle to gate. One of the most representative categories, climate change, places the average environmental impact in 2.43 kg CO2 eq/kg, while the range is between 1.93 and 3.00 kg CO2 eq/kg depending on the harvest. Huge differences between values are observed in the farming phase and they are mostly caused by the virgin olive oil yield of every harvest. The carbon sequestration analyses and the impact produced per FU ranges from 43.78% (for 15/16 harvest) to 46.36% (for 17/18). The impact hotspots detected in the farming phase, in terms of climate change potential, are the categories of plant protection products and herbicides (24.11% of the average value) and fertilizers (20.01%). However, the environmental impact of the industrial phase is relatively constant, with a value of 0.547-0.554 kg of CO2 equivalent. The 80.74% is caused by pomace valorization, which translated to the average whole value, represents the 18.56%. (C) 2020 Elsevier Ltd. All rights reserved.

Recommanded Product: 1-Phenylurea. Welcome to talk about 64-10-8, If you have any questions, you can contact Fernandez-Lobato, L; Lopez-Sanchez, Y; Blejman, G; Jurado, F; Moyano-Fuentes, J; Vera, D or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Name: 1-Phenylurea. Recently I am researching about ANION-BINDING; TRIAZOLE DERIVATIVES; SCHIFF-BASES; 1,3,4-THIADIAZOLE; 1,2,4-TRIAZOLE; MOTIF, Saw an article supported by the . Published in WILEY in HOBOKEN ,Authors: Yusuf, M; Thakur, S. The CAS is 64-10-8. Through research, I have a further understanding and discovery of 1-Phenylurea

A new series of 1,2,4-triazole was designed, synthesized, and characterized as remarkable antimicrobial and antioxidant agents. These heterocycles have been prepared from the cyclization reactions of Schiff bases 3(a-k) with phenylhydrazine by refluxing under the alkaline medium. The Schiff bases in turn were realized in good yields from the condensation reactions of N-phenylurea with different aromatic aldehydes. The structures of the intermediates 3(a-k) and final heterocycles 4(a-k) have been fully characterized through their spectral parameters.

Name: 1-Phenylurea. Welcome to talk about 64-10-8, If you have any questions, you can contact Yusuf, M; Thakur, S or send Email.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem