Category: Thiomorpholine

In 2020.0 ECOTOX ENVIRON SAFE published article about PHENYL-UREA HERBICIDES; PLATINUM NANOPARTICLES; CARBON NANOTUBES; ELECTROCHEMICAL SENSOR; GRAPHITE ELECTRODE; WATER SAMPLES; CHITOSAN; PERFORMANCE; PESTICIDES; OXIDATION in [Morawski, Franciele de Matos; Winiarski, Joao Paulo; Parize, Alexandre Luis; Jost, Cristiane Luisa] Univ Fed Santa Catarina, Dept Quim, Ampere Lab Plataformas Eletroquim, BR-88040900 Florianopolis, SC, Brazil; [Maduro de Campos, Carlos Eduardo] Univ Fed Santa Catarina, Dept Fis, BR-88040900 Florianopolis, SC, Brazil in 2020.0, Cited 60.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8. Recommanded Product: 1-Phenylurea

Phenylurea herbicides are persistent contaminants, which leads their transport to the surface and ground waters, affecting human and aquatic organisms. Different analytical methods have been reported for the detection of phenylureas; however, several of them are expensive, time-consuming, and require complex pretreatment steps. Here, we show a simple method for the simultaneous electrochemical determination of two phenylurea herbicides by differential pulse adsorptive stripping voltammetry (DPAdSV) using a modified platinum/chitosan electrode. The one-step synthesized platinum/chitosan PtNPs/CS was successfully characterized by TEM, XRPD, and FT-IR, and applied through the sensing platform designated as PtNPs/CS/GCE. This bio-based modified electrode is proposed for the first time for the individual and/or simultaneous electrochemical detection of the phenylurea herbicides diuron and isoproturon compounds extensively used worldwide that present a very similar chemical structure. Electrochemical and interfacial characteristics of the modified electrode were evaluated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). It was found that the oxidation mechanism of diuron and isoproturon occurs in two different pathways, with a peak-to-peak definition of ca. 0.15 V. Under differential pulse adsorptive stripping voltammetry (DPAdSV) optimized conditions, the limit of detection (LOD) was estimated as 7 mu g L-1 for isoproturon and 20 mu g L-1 for diumn (E-d = +0.8 V; t(d) = 100 s). The proposed method was successfully applied to the determination of both analytes in river water samples, at three different levels, with a recovery range of 90-110%. The employment of the bio-based sensing platform PtNPs/CS/GCE allows a novel and easy analytical method to the multi-component phenylurea herbicides detection.

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In 2019.0 LUNG CANCER published article about NSCLC; CHEMOTHERAPY; DOCETAXEL; SYSTEM in [Crino, Lucio; Bronte, Giuseppe; Cravero, Paola; Delmonte, Angelo] Ist Sci Romagnolo Studio & Cura Tumori IRST IRCCS, Meldola, Italy; [Bidoli, Paolo] Osped San Gerardo, Monza, Italy; [Minenza, Elisa] AO Santa Maria, Terni, Italy; [Cortesi, Enrico] Policlin Umberto 1, Rome, Italy; [Garassino, Marina C.; Proto, Claudia] Fdn IRCCS Ist Nazl Tumori, Milan, Italy; [Cappuzzo, Federico] AUSL Romagna, Ravenna, Italy; [Grossi, Francesco] IRCCS AOU San Martino IST, Genoa, Italy; [Tonini, Giuseppe] Policlin Univ Campus Biomed, Rome, Italy; [Sarobba, Maria Giuseppina] ASL 3 S Francesco, Nuoro, Italy; [Pinotti, Graziella] Osped Circolo & Fdn Macchi, Varese, Italy; [Numico, Gianmauro] AO SS Antonio & Biagio & C Arrigo, Alessandria, Italy; [Samaritani, Riccardo] Presidio Nuovo Regina Margherita, Rome, Italy; [Ciuffreda, Libero] AOU Citta Salute & Sci Torino, Turin, Italy; [Frassoldati, Antonio] Arcispedale S Anna Ferrara, Ferrara, Italy; [Bregni, Marco] Presidio Osped Busto Arsizio, Varese, Italy; [Santo, Antonio] AO Univ Integrata Verona, Verona, Italy; [Piantedosi, Francovito; Illiano, Alfonso] AO Colli, Monaldi Cotugno CTO, Naples, Italy; [De Marinis, Filippo] European Inst Oncol, Milan, Italy; [Tamberi, Stefano] Infermi Hosp, Faenza, Italy; [Giannarelli, Diana] Regina Elena Natl Canc Inst IRCCS, Rome, Italy in 2019.0, Cited 22.0. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8. Product Details of 64-10-8

Objectives: Brain metastases are common among patients with non-squamous non-small-cell lung cancer (NSCLC) and result in a poor prognosis. Consequently, such patients are often excluded from clinical trials. In Italy an expanded access program (EAP) was used to evaluate nivolumab efficacy and safety in this sub population outside a clinical trial. Materials and methods: In this EAP, nivolumab was available for patients with non-squamous NSCLC in progression after at least one systemic treatment for stage IIIB/IV disease. Nivolumab 3 mg/kg was administered intravenously every 2 weeks. Patients with brain metastases could be included if they were asymptomatic, neurologically stable and either off corticosteroids or on a stable or decreasing dose of <= 10 mg/day prednisone. Results: 409 out of 1588 patients included had asymptomatic or controlled brain metastases. A median of 7 doses (range 1-45) were delivered. Median follow-up was 6.1 months (range 0.1-21.9). The disease control rate was 39%: 4 patients had a complete response, 64 a partial response and 96 showed stable disease. At baseline, 118 patients were on corticosteroids and 74 were undergoing concomitant radiotherapy. The median overall survival in this subpopulation was 8.6 months (95% CI: 6.4-10.8). 337 discontinued treatment for various reasons, 23 (7%) of whom due to adverse events, in line with that observed in the overall population and in previous studies. Conclusions: Our results confirm that nivolumab is active in non-squamous NSCLC patients with brain metastases, despite their poor prognosis. Its safety profile is also concordant with results in the EAP overall population and in patients with other malignancies. Welcome to talk about 64-10-8, If you have any questions, you can contact Crino, L; Bronte, G; Bidoli, P; Cravero, P; Minenza, E; Cortesi, E; Garassino, MC; Proto, C; Cappuzzo, F; Grossi, F; Tonini, G; Sarobba, MG; Pinotti, G; Numico, G; Samaritani, R; Ciuffreda, L; Frassoldati, A; Bregni, M; Santo, A; Piantedosi, F; Illiano, A; De Marinis, F; Tamberi, S; Giannarelli, D; Delmonte, A or send Email.. Product Details of 64-10-8

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Thiomorpholine – Wikipedia,
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An article Rhodium-Catalyzed One-Pot Access to N-Polycyclic Aromatic Hydrocarbons from Aryl Ketones through Triple C-H Bond Activations WOS:000606840200091 published article about DOPED GRAPHENE; FUNCTIONALIZATION; MULTIPLE; ELECTROCATALYSTS; TRANSISTORS; ANNULATION; CLEAVAGE; CASCADE in [Biswal, Pragati; Banjare, Shyam Kumar; Pati, Bedadyuti Vedvyas; Mohanty, Smruti Ranjan; Ravikumar, Ponneri Chandrababu] HBNI, Natl Inst Sci Educ & Res NISER Bhubaneswar, Sch Chem Sci, Khurja 752050, Odisha, India in 2021.0, Cited 44.0. COA of Formula: C13H10O. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

A Rh-catalyzed pot and step economic synthesis of aza-polycyclic aromatic hydrocarbons (N-PAHs) from readily available aryl ketones and alkynes has been disclosed. Additionally, a novel synthetic application of the well-known aminating reagent hydroxylamine-O-sulfonic acid (HOSA) has been explored as an in situ redox-neutral directing group for the formation of N-PAHs via isoquinoline. Multiple bond formation in a single operation through a cascade of triple C-H bond activations is the beauty of this protocol. The challenging annulations of two different alkynes in a regioselective fashion have been demonstrated effectively. Mechanistic studies reveal that 3,4-diphenyl-1-methylisoquinoline is an active intermediate for this one-pot transformation.

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An article Synthesis of tricyclic quinazolinone-iminosugars as potential glycosidase inhibitors via a Mitsunobu reaction WOS:000468101000002 published article about PHARMACOLOGICAL CHAPERONES; DESIGN; AZASUGARS; ENZYMES in [Sun, Jiajing; Kang, Yaqing; Gao, Ligang; Lu, Xin; Ju, Huanhuan; Li, Xiaoliu; Chen, Hua] Hebei Univ, Coll Chem & Environm Sci, Key Lab Chem Biol Hebei Prov, Baoding 071002, Peoples R China in 2019, Cited 37. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6. Category: thiomorpholine

A series of novel tricyclic quinazolinone-iminosugars 1 (a-c) were synthesized from the benzyl protected sugars through three steps. Firstly, the benzyl protected sugar (aldehyde) 5 reacted with o-aminobenzamide by the iodine-induced oxidative condensation to afford the corresponding aldo-quizanolinone 6. Secondly, through the intramolecular cyclization of the unprotected OH and the amide NH in 6, the tricyclic compounds 7 and 8 were constructed by the key Mitsunobu reaction. Finally, removal of the benzyl group gave the target tricyclic quinazolinone-iminosugars 1. The protocol was effective for the preparation of the tricyclic iminosugars in satisfactory yield. Interestingly, an unusual C-2 epimerization was observed with D-mannose and D-ribose compounds under the conditions of the Mitsunobu reaction that generated the products having the trans configuration at the C-2 and C-3 positions. Unfortunately, such tricyclic quinazolinone-iminosugars showed no inhibitory effects on the tested five glycosidases.

Category: thiomorpholine. Welcome to talk about 88-68-6, If you have any questions, you can contact Sun, JJ; Kang, YQ; Gao, LG; Lu, X; Ju, HH; Li, XL; Chen, H or send Email.

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Authors Zhang, H; Guo, TY; Wu, MZ; Huo, X; Tang, SC; Wang, XL; Liu, J in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Zhang, Heng; Guo, Tianyun; Tang, Shouchu; Liu, Jian] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China; [Wu, Mingzhong; Huo, Xing; Wang, Xiaolei] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China in 2021.0, Cited 42.0. Application In Synthesis of Benzophenone. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

A green photoredox oxidation of benzylic primary and secondary alcohols to aldehydes and ketones with air as an oxidant was reported. The oxidation shows broad substrate scope and excellent selectivity over benzylic alcohols to the aliphatic alcohols. Further mechanistic studies revealed a quinuclidine mediated HAT process, and blue LEDs promoted 4CzIPN (1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene) photoredox cycle were involved in our oxidation. (C) 2021 Elsevier Ltd. All rights reserved.

Welcome to talk about 119-61-9, If you have any questions, you can contact Zhang, H; Guo, TY; Wu, MZ; Huo, X; Tang, SC; Wang, XL; Liu, J or send Email.. Application In Synthesis of Benzophenone

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Thiomorpholine – Wikipedia,
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An article Synthesis of Various 2-Aminobenzoxazoles: The Study of Cyclization and Smiles Rearrangement WOS:000497960900041 published article about BENZOXAZOLE DERIVATIVES; BIOLOGICAL EVALUATION; DIRECT AMINATION; DESIGN; ANTICANCER; CYANATION in [Slachtova, Veronika; Chasak, Jan; Brulikova, Lucie] Palacky Univ Olomouc, Fac Sci, Dept Organ Chem, 17 Listopadu 12, Olomouc 77146, Czech Republic in 2019.0, Cited 38.0. SDS of cas: 64-10-8. The Name is 1-Phenylurea. Through research, I have a further understanding and discovery of 64-10-8

This study reports two synthetic approaches leading to 2-aminobenzoxazoles and their N-substituted analogues. Our first synthetic strategy involves a reaction between various o-aminophenols and N-cyano-N-phenyl-p-toluenesulfonamide as a nonhazardous electrophilic cyanating agent in the presence of Lewis acid. The second synthetic approach uses the Smiles rearrangement upon activation of benzoxazole-2-thiol with chloroacetyl chloride. Both developed synthetic protocols are widely applicable, afford the desired aminobenzoxazoles in good to excellent yields, and use nontoxic and inexpensive starting material.

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Thiomorpholine – Wikipedia,
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Authors Zhang, XY; Wei, DB; Sun, XF; Bai, CZ; Du, YG in ELSEVIER SCI LTD published article about DISINFECTION BY-PRODUCTS; NATURAL ORGANIC-MATTER; WATER CHLORINATION; ECOLOGICAL RISKS; KINETICS; TRANSFORMATION; TOXICITY; ACIDS; TRIHALOMETHANES; IDENTIFICATION in [Zhang, Xinyi; Wei, Dongbin; Sun, Xuefeng; Bai, Chenzhong; Du, Yuguo] Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China; [Zhang, Xinyi; Wei, Dongbin; Sun, Xuefeng; Bai, Chenzhong; Du, Yuguo] Univ Chinese Acad Sci, Beijing 100049, Peoples R China in 2021, Cited 41. Name: Benzophenone. The Name is Benzophenone. Through research, I have a further understanding and discovery of 119-61-9

Chloroform, a regulated disinfection by-product in water, is often generated during chlorination disinfection treatment. However, the formation of chloroform is heavily dependent on the molecular structures of precursors. Moreover, compounds containing ketone moiety are ubiquitous in water environments. However, it is unclear if they can generate chloroform during chlorination. In this study, 14 benzophenones (BPs), efficient and widely used UV filters, with different substituents were selected to explore chloroform formation during chlorination. All 14 BPs generated chloroform, with yields dependent on their molecular structures and operational conditions. Compounds 2,2′,4,4′-tetrahydroxy-BP and benzophenone produced the highest and lowest chloroform of 0.313 and 0.013 g/g, respectively, corresponding to the fastest and slowest formation rate constants of 1.41 x 10(-1) and 2.71 x 10(-2) min(-1). Alkaline conditions and high chlorine dosages were favorable to chloroform formation. Three reactions played key roles in chloroform formation from BPs: (1) chlorine initiated Baeyer Villiger oxidation converted ketone moieties of BP molecules into esters; (2) the esters further underwent hydrolysis and formed phenolic and benzoic products; and (3) benzoic acids underwent decarboxylation and hydrolysis to form phenolic products. Subsequently, these phenolic products could further generate chloroform in the chlorination system. More importantly, BPs could generate chloroform in the ambient water matrices during practical chlorination treatment. This work emphasized the critical role of Baeyer-Villiger oxidation for chloroform formation, implying that pollutants containing aromatic ketone moieties generate chloroform during chlorination disinfection, and their potential risk should therefore be reviewed. (C) 2020 Elsevier Ltd. All rights reserved.

Name: Benzophenone. Bye, fridends, I hope you can learn more about C13H10O, If you have any questions, you can browse other blog as well. See you lster.

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Thiomorpholine – Wikipedia,
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An article Metabolic syndrome risk in relation to posttraumatic stress disorder among trauma-exposed civilians in Gansu Province, China WOS:000525863600052 published article about CORONARY-HEART-DISEASE; INSULIN-RESISTANCE; SYMPTOMS; PTSD; PEOPLE; CHECKLIST; BEHAVIOR; OBESITY; GENDER; IMPACT in [Ma LIhua; Jiang Xiaolian] Sichuan Univ, Inst Emergency Management & Reconstruct Postdisas, Chengdu, Peoples R China; [Zhang Tao] 940 Hosp Joint Logist Support Force Chinese Peopl, Dept Spine Surg, Lanzhou, Peoples R China; [Ma Hongbi] Northwest Minzu Univ, Sch Civil Engn, Lanzhou, Peoples R China; [Ma LIhua; Wang Hui] Lanzhou Univ, Hosp 1, Lanzhou, Peoples R China; [Jiao Caihong] First Hosp Long Nan City, Lanzhou, Gansu, Peoples R China; [Jiang Xiaolian] Sichuan Univ, West China Hosp, Nursing Dept, Chengdu 610041, Peoples R China in 2020, Cited 36. Computed Properties of C10H12O3. The Name is 4-Methoxybenzyl acetate. Through research, I have a further understanding and discovery of 104-21-2

This study included 1456 men and 1411 women who were trauma-exposed and underwent routine health examinations in a community epidemiological investigation. The participants completed the posttraumatic stress disorder (PTSD) Check List-Civilian Version (PCL-C) for PTSD and medical examinations to detect metabolic syndrome. Adjustments for age, marriage, exercise, education, cigarette smoking, cancer, stroke, angina, and thyroid disease were performed. The relationship between PTSD and metabolic syndrome and each of its components was analyzed by multiple logistic regression. In women, PTSD was associated with metabolic syndrome (OR = 1.53, 95% CI = 1.01-1.95, P = .047) and the high-density lipoprotein cholesterol component (OR = 1.98, 95% CI = 1.04-2.12, P = .002). In men, PTSD was related to the hypertension component of metabolic syndrome (OR = 0.54, 95% CI = 0.31-0.92, P = .023). There was also a relationship between PTSD severity and metabolism (OR = 1.141, 95% CI = 1.002-1.280, P = 0.037) in women, and PTSD was inversely associated with the hypertension component (OR = 0.54, 95% CI = 0.31-0.92, P = .023) in men. PTSD was related to metabolic syndrome only in women. We plan to further research the mechanism of sex differences and dyslipidemia.

Welcome to talk about 104-21-2, If you have any questions, you can contact Ma, LH; Zhang, T; Ma, HB; Wang, H; Jiao, CH; Jiang, XL or send Email.. Computed Properties of C10H12O3

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Thiomorpholine – Wikipedia,
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Recommanded Product: 119-61-9. Recently I am researching about N-HETEROCYCLIC CARBENE; C-C; BORROWING HYDROGEN; CLEAVAGE; KETONES; OLEFIN; FUNCTIONALIZATION; METATHESIS; ALDEHYDES; INSERTION, Saw an article supported by the European Research Council (ERC)European Research Council (ERC)European Commission [757608]; Swiss National Science Foundation (SNF)Swiss National Science Foundation (SNSF) [184658]; ETH ZurichETH Zurich; German Academic Scholarship Foundation. Published in CELL PRESS in CAMBRIDGE ,Authors: Lutz, MDR; Gasser, VCM; Morandi, B. The CAS is 119-61-9. Through research, I have a further understanding and discovery of Benzophenone

The advent of transfer hydrogenation and borrowing hydrogen reactions paved the way to manipulate simple alcohols in previously unthinkable manners and circumvented the need for hydrogen gas. Analogously, transfer hydrocarbylation could greatly increase the versatility of tertiary alcohols. However, this reaction remains unexplored because of the challenges associated with the catalytic cleavage of unactivated C-C bonds. Herein, we report a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp(2))-C(sp(3)) bond in unstrained triaryl alcohols via a redox-neutral beta-carbon elimination mechanism. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcohols to ketones was realized, employing benign alcohols as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible b-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcohols in catalysis.

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Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Gold(i)-NHC-catalysed synthesis of benzofuransviamigratory cyclization of 2-alkynylaryl ethers WOS:000580494600017 published article about C-N BOND; SILVER-FREE; 2,3-DISUBSTITUTED BENZOFURANS; CATALYZED CYCLIZATION; GOLD CATALYSIS; COMPLEXES; ALKYNES; CARBOALKOXYLATION; CARBOTHIOLATION; REACTIVITY in [Le, Quang; Dillon, Christopher C.; Lichtenstein, Dana A.; Pisor, Jeremy W.; Closser, Kristina D.; Muchalski, Hubert] Calif State Univ Fresno, 2555 E San Ramon Ave M-S SB70, Fresno, CA 93740 USA in 2020, Cited 46. Recommanded Product: 104-21-2. The Name is 4-Methoxybenzyl acetate. Through research, I have a further understanding and discovery of 104-21-2

Homogeneous cationic gold(i) catalysis emerged as a preferred avenue for the activation of alkenes and alkynes towards reactions with weak nucleophiles, especially in cyclization reactions. Here we report an intramolecular carboalkoxylation reaction of electron-rich benzyl ethers of 2-ethynylaryl phenols catalysed by a digold(i)-NHC complex. The reaction proceeds efficiently with low catalyst loading and the resulting 2,3-disubstituted benzofurans form in moderate to good yields. Based on the results of a cross-over experiment, spectroscopic data, and DFT calculations, we propose a mechanism that accounts for the observed chemo- and regioselectivity.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem