Category: 90-44-8

Safety of Anthrone. Recently I am researching about AROMATIC POLYAMIDES; POLYIMIDES; ETHER; UNIT, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21564005, 51663011]; Research Program of Jiangxi Science and Technology Department [20192BBE50049]; Ground Project for Science and Technology of Jiangxi Universities [KJLD14022]; Research Program of Jiangxi Province Department of Education [GJJ14236]. Published in TAYLOR & FRANCIS INC in PHILADELPHIA ,Authors: Zhou, YF; Huang, ZZ; Mao, XC; Song, C. The CAS is 90-44-8. Through research, I have a further understanding and discovery of Anthrone

A new aromatic diamine, 10,10-bis [4-(4-amino-2-pyridinoxy)phenyl]-9(10H)-anthracenone (BAPPA) was synthesized from anthrone as the starting material, and the corresponding pyridine- and anthrone-containing poly(ether amide)s (PEAs) were prepared from BAPPA with various aromatic diacid chlorides via a low-temperature solution polycondensation. The resulting PEAs having number-average molecular weights (M-n) of 29,500-33,400 g/mol with the polydispersity index ranged from 1.75 to 1.84, were all amorphous, and displayed excellent thermal stability with the glass transition temperatures of 263-355 degrees C, the temperatures of 415-441 degrees C at 5% weight loss and the higher than 50% residues at 800 degrees C in nitrogen. These new PEAs were soluble in polar solvents such as N-methyl-2-pyrrolidone, N,N-dimethylacetamide and pyridine, even almost in tetrahydrofuran at room temperature and could form transparent, strong and flexible films with tensile strengths of 84-97 MPa, tensile moduli of 2.1-3.2 GPa and elongations at break of 4-13%. Also, the present PEAs exhibited high optical transparence with the UV cutoff wavelength in the 342-362 nm range, and 83-90% transmittance at 500 nm. These results indicated the introduction of anthrone and pyridine groups into the backbone could improve the solubility and transparence of polyamides.

About Anthrone, If you have any questions, you can contact Zhou, YF; Huang, ZZ; Mao, XC; Song, C or concate me.. Safety of Anthrone

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Bioactive naphthoquinone and anthrone derivatives from endophytic Micromonospora sp. NEAU-gq13 WOS:000500123000002 published article about FUNGI in [Li, Jian-Song; Zhang, Hui; Qi, Huan; Wang, Ji-Dong] Zhejiang Hisun Pharmaceut Co Ltd, Zhejiang Key Lab Antifungal Drugs, Taizhou 318000, Peoples R China; [Xiang, Wen-Sheng] Northeast Agr Univ, Sch Life Sci, Life Sci & Biotechnol Res Ctr, Harbin 150030, Heilongjiang, Peoples R China in 2019, Cited 16. Recommanded Product: 90-44-8. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Two new naphthalenone derivatives, 5-hydroxy-4-oxo-2-(2-oxopropyl)-1,2,3,4-tetrahydronaphthalen-1-yl acetate (1) and 5-hydroxy-2-(2-hydroxypropyl)naphthalene-1,4-dione (2), together with two new anthrone derivatives, (S)-2,5-dihydroxy-2-methyl-1,2,3,4-tetrahydroanthracene-9,10-dione (3) and 4,5-dihydroxy-2-methyl-9H-xanthen-9-one (4), were isolated from the fermentation broth of endophytic Micromonospora sp. NEAU-gq13. Their structures were determined by 1D-NMR, 2D-NMR, and HR-ESI-MS analysis. Compounds 2 and 3 exhibited strong cytotoxic activity against human central nervous system cancer (SF-268) with the IC50 values of 3.04 and 5.66 mu g/ml, respectively. Moreover, compound 2 also displayed potent activity against human liver cancer (HepG2) with an IC50 value of 1.01 mu g/ml.

Recommanded Product: 90-44-8. About Anthrone, If you have any questions, you can contact Li, JS; Zhang, H; Qi, H; Wang, JD; Xiang, WS or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Recommanded Product: 90-44-8. Recently I am researching about INDUCE APOPTOSIS; PHOTOCHEMICAL ISOMERIZATION; TRICYCLIC ANTIDEPRESSANTS; CELL-PROLIFERATION; ADULT BURKITT; NITROSTYRENE; DEAMINATION; DERIVATIVES; ACTIVATION; LEUKEMIA, Saw an article supported by the Trinity College Dublin. Published in MDPI in BASEL ,Authors: Byrne, AJ; Bright, SA; McKeown, JP; O’Brien, JE; Twamley, B; Fayne, D; Williams, DC; Meegan, MJ. The CAS is 90-44-8. Through research, I have a further understanding and discovery of Anthrone

Lymphomas (cancers of the lymphatic system) account for 12% of malignant diseases worldwide. Burkitt’s lymphoma (BL) is a rare form of non-Hodgkin’s lymphoma in which the cancer starts in the immune B-cells. We report the synthesis and preliminary studies on the antiproliferative activity of a library of 9,10-dihydro-9,10-ethanoanthracene based compounds structurally related to the antidepressant drug maprotiline against BL cell lines MUTU-1 and DG-75. Structural modifications were achieved by Diels-Alder reaction of the core 9-(2-nitrovinyl)anthracene with number of dienophiles including maleic anhydride, maleimides, acrylonitrile and benzyne. The antiproliferative activity of these compounds was evaluated in BL cell lines EBV- MUTU-1 and EBV+ DG-75 (chemoresistant). The most potent compounds 13j, 15, 16a, 16b, 16c, 16d and 19a displayed IC50 values in the range 0.17-0.38 mu M against the BL cell line EBV- MUTU-1 and IC50 values in the range 0.45-0.78 mu M against the chemoresistant BL cell line EBV+ DG-75. Compounds 15, 16b and 16c demonstrated potent ROS dependent apoptotic effects on the BL cell lines which were superior to the control drug taxol and showed minimal cytotoxicity to peripheral blood mononuclear cells (PBMCs). The results suggest that this class of compounds merits further investigation as antiproliferative agents for BL.

About Anthrone, If you have any questions, you can contact Byrne, AJ; Bright, SA; McKeown, JP; O’Brien, JE; Twamley, B; Fayne, D; Williams, DC; Meegan, MJ or concate me.. Recommanded Product: 90-44-8

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

I found the field of Chemistry very interesting. Saw the article Stoichiometric Formation of an Oxoiron(IV) Complex by a Soluble Methane Monooxygenase Type Activation of O-2 at an Iron(II)-Cyclam Center published in 2020. Recommanded Product: Anthrone, Reprint Addresses Ray, K (corresponding author), Humboldt Univ, Inst Chem, D-12489 Berlin, Germany.. The CAS is 90-44-8. Through research, I have a further understanding and discovery of Anthrone

In soluble methane monooxygenase enzymes (sMMO), dioxygen (O-2) is activated at a diiron(II) center to form an oxodiiron(IV) intermediate Q that performs the challenging oxidation of methane to methanol. An analogous mechanism of O-2 activation at mono- or dinuclear iron centers is rare in the synthetic chemistry. Herein, we report a mononuclear non-heme iron(II)cyclam complex, 1-trans, that activates O-2 to form the corresponding iron(IV)-oxo complex, 2-trans, via a mechanism reminiscent of the O-2 activation process in sMMO. The conversion of 1-trans to 2-trans proceeds via the intermediate formation of an iron(III)-superoxide species 3, which could be trapped and spectroscopically characterized at -50 degrees C. Surprisingly, 3 is a stronger oxygen atom transfer (OAT) agent than 2-trans; 3 performs OAT to 1-trans or PPh 3 to yield 2-trans quantitatively. Furthermore, 2-trans oxidizes the aromatic C-H bonds of 2,6-di-tert-butylphenol, which, together with the strong OAT ability of 3, represents new domains of oxoiron(IV) and superoxoiron(III) reactivities.

Recommanded Product: Anthrone. About Anthrone, If you have any questions, you can contact Kass, D; Corona, T; Warm, K; Braun-Cula, B; Kuhlmann, U; Bill, E; Mebs, S; Swart, M; Dau, H; Haumann, M; Hildebrandt, P; Ray, K or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Nontarget Screening of Polycyclic Aromatic Compounds in Atmospheric Particulate Matter Using Ultrahigh Resolution Mass Spectrometry and Comprehensive Two-Dimensional Gas Chromatography WOS:000606821200012 published article about FT-ICR MS; HYDROCARBONS PAHS; MOLECULAR CHARACTERIZATION; AIRBORNE PARTICLES; OXYGENATED-PAHS; IDENTIFICATION; EMISSIONS; PM2.5; QUANTIFICATION; CONTAMINANTS in [Xu, Chi; Gao, Lirong; Zheng, Minghui; Qiao, Lin; Wang, Kunran; Huang, Di; Wang, Shuang] Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China; [Xu, Chi; Gao, Lirong; Zheng, Minghui; Qiao, Lin; Wang, Kunran; Huang, Di; Wang, Shuang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China in 2021, Cited 45. Application In Synthesis of Anthrone. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Polycyclic aromatic hydrocarbons (PAHs) are mutagenic and carcinogenic. 16 PAHs as priority pollutants listed by the US Environmental Protection Agency were usually monitored. Therefore, multiple potentially toxic polycyclic aromatic compounds (PACs) are not monitored. In this study, atmospheric particulate matter samples from Beijing were analyzed using atmospheric pressure photoionization (APPI) Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry and comprehensive two-dimensional gas chromatography-time-of-flight (GC x GC-TOF) mass spectrometry. The FT-ICR data detected high molecular weight PAHs, alkylated PAHs (APAHs) and heteroatom PAHs. The GC x GC-TOF data tentatively identified 386 PACs in five categories of identification confidence. Twenty-one spectra in the unknown class were manually resolved. Eighty-two PACs with high identification confidence were proposed for further research. The identities of five PAHs and five APAHs that are currently not regulated were confirmed using available standards and quantified in some samples. Some of these PACs, such as dibenzo[a,e]pyrene (C22H14) and 1-methylpyrene (C17H12), should be of concern because of their contamination levels and the high toxicities of themselves and/or their derivatives. This study highlights the possibility of expanding the traditional lists of PAHs to improve pollution control and risk assessment accuracy.

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Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

In 2021 INORG CHIM ACTA published article about ZETA VALENCE QUALITY; GAUSSIAN-BASIS SETS; COPPER(II) COMPLEXES; CATALYTIC MECHANISM; BETA-MONOOXYGENASE; OLEFIN EPOXIDATION; COMPOUND I; ATOMS LI; OXO; MONONUCLEAR in [Khazanov, Thomas M.; Botcha, Niharika Krishna; Mukherjee, Anusree] Univ Alabama, Dept Chem, 301 Sparkman Dr, Huntsville, AL 35899 USA; [Yergeshbayeva, Sandugash; Shatruk, Michael] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA in 2021, Cited 88. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8. Formula: C14H10O

This work presents a detailed study of the reactivity of three mononuclear Cu-II complexes supported by derivatives of the tetradentate ligand N,N’-bis(2-pyridylmethyl)-1,2-ethylenediamine (bispicen). The Cu-II complexes are capable of performing C – H bond activation in the presence of NEt3 and H2O2 through what has been proposed computationally to be a [CuO](+) intermediate. A wavefunction-based quantum chemical investigation into the electronic structure of the proposed [CuO](+) intermediate reveals a triplet ground state predominantly consistent with an S = 1/2 Cu-II center ferromagnetically coupled to an oxyl radical, though contributions from the corresponding biradicaloid CM-oxen resonance structure may be nontrivial. Furthermore, correlation of the electronic structure of the proposed intermediate with analogous high-valent metal-oxo species capable of olefin epoxidation suggests that the Cu-II complexes might be also capable of olefin epoxidation in the presence of NEt3 and H2O2. To test this hypothesis experimentally, the Cu-II complexes are treated with NEt 3 and H2O2 in the presence of alkene substrates, resulting in the formation of epoxides.

About Anthrone, If you have any questions, you can contact Khazanov, TM; Botcha, NK; Yergeshbayeva, S; Shatruk, M; Mukherjee, A or concate me.. Formula: C14H10O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Authors Abouelela, ME; Assaf, HK; Abdelhamid, RA; Elkhyat, ES; Sayed, AM; Oszako, T; Belbahri, L; El Zowalaty, AE; Abdelkader, MSA in MDPI published article about VAR NATALENSIS BERGER; CHEMICAL-CONSTITUENTS; SAPONARIA-HAW; TETRAHYDROANTHRACENE DERIVATIVES; STRUCTURE ELUCIDATION; C-GLUCOSYLANTHRONES; CHROMONE COMPONENTS; MOLECULAR-DYNAMICS; ANTIVIRAL ACTIVITY; CALLUS-TISSUE in [Abouelela, Mohamed E.; Assaf, Hamdy K.; Abdelhamid, Reda A.; Elkhyat, Ehab S.] Al Azhar Univ, Fac Pharm, Dept Pharmacognosy, Assiut Branch, Assiut 71524, Egypt; [Sayed, Ahmed M.] Nanda Univ, Fac Pharm, Dept Pharmacognosy, Bani Suwayf 62513, Egypt; [Oszako, Tomasz] Forest Res Inst, Dept Forest Protect, PL-05090 Sekocin Stary, Poland; [Belbahri, Lassaad] Univ Neuchatel, Lab Soil Biol, CH-2000 Neuchatel, Switzerland; [El Zowalaty, Ahmed E.] Univ Gothenburg, Sahlgrenska Ctr Canc Res, Inst Clin Sci, Dept Surg, S-40530 Gothenburg, Sweden; [El Zowalaty, Ahmed E.] Univ Gothenburg, Wallenberg Ctr Mol & Translat Med, S-40530 Gothenburg, Sweden; [Abdelkader, Mohamed Salaheldin A.] Sohag Univ, Fac Pharm, Dept Pharmacognosy, Nasr City 82524, Sohag, Egypt in 2021, Cited 182. SDS of cas: 90-44-8. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) disease is a global rapidly spreading virus showing very high rates of complications and mortality. Till now, there is no effective specific treatment for the disease. Aloe is a rich source of isolated phytoconstituents that have an enormous range of biological activities. Since there are no available experimental techniques to examine these compounds for antiviral activity against SARS-CoV-2, we employed an in silico approach involving molecular docking, dynamics simulation, and binding free energy calculation using SARS-CoV-2 essential proteins as main protease and spike protein to identify lead compounds from Aloe that may help in novel drug discovery. Results retrieved from docking and molecular dynamics simulation suggested a number of promising inhibitors from Aloe. Root mean square deviation (RMSD) and root mean square fluctuation (RMSF) calculations indicated that compounds 132, 134, and 159 were the best scoring compounds against main protease, while compounds 115, 120, and 131 were the best scoring ones against spike glycoprotein. Compounds 120 and 131 were able to achieve significant stability and binding free energies during molecular dynamics simulation. In addition, the highest scoring compounds were investigated for their pharmacokinetic properties and drug-likeness. The Aloe compounds are promising active phytoconstituents for drug development for SARS-CoV-2.

About Anthrone, If you have any questions, you can contact Abouelela, ME; Assaf, HK; Abdelhamid, RA; Elkhyat, ES; Sayed, AM; Oszako, T; Belbahri, L; El Zowalaty, AE; Abdelkader, MSA or concate me.. SDS of cas: 90-44-8

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Product Details of 90-44-8. Li, JS; Zhang, H; Qi, H; Wang, JD; Xiang, WS in [Li, Jian-Song; Zhang, Hui; Qi, Huan; Wang, Ji-Dong] Zhejiang Hisun Pharmaceut Co Ltd, Zhejiang Key Lab Antifungal Drugs, Taizhou 318000, Peoples R China; [Xiang, Wen-Sheng] Northeast Agr Univ, Sch Life Sci, Life Sci & Biotechnol Res Ctr, Harbin 150030, Heilongjiang, Peoples R China published Bioactive naphthoquinone and anthrone derivatives from endophytic Micromonospora sp. NEAU-gq13 in 2019, Cited 16. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

Two new naphthalenone derivatives, 5-hydroxy-4-oxo-2-(2-oxopropyl)-1,2,3,4-tetrahydronaphthalen-1-yl acetate (1) and 5-hydroxy-2-(2-hydroxypropyl)naphthalene-1,4-dione (2), together with two new anthrone derivatives, (S)-2,5-dihydroxy-2-methyl-1,2,3,4-tetrahydroanthracene-9,10-dione (3) and 4,5-dihydroxy-2-methyl-9H-xanthen-9-one (4), were isolated from the fermentation broth of endophytic Micromonospora sp. NEAU-gq13. Their structures were determined by 1D-NMR, 2D-NMR, and HR-ESI-MS analysis. Compounds 2 and 3 exhibited strong cytotoxic activity against human central nervous system cancer (SF-268) with the IC50 values of 3.04 and 5.66 mu g/ml, respectively. Moreover, compound 2 also displayed potent activity against human liver cancer (HepG2) with an IC50 value of 1.01 mu g/ml.

Product Details of 90-44-8. About Anthrone, If you have any questions, you can contact Li, JS; Zhang, H; Qi, H; Wang, JD; Xiang, WS or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

Formula: C14H10O. Zhou, YF; Huang, ZZ; Mao, XC; Song, C in [Zhou, Yi-Fang; Huang, Zhen-Zhong; Mao, Xue-Chun; Song, Cheng] Jiangxi Normal Univ, Minist Educ, Key Lab Funct Small Organ Mol, Nanchang, Jiangxi, Peoples R China published Highly transparent and organosoluble poly(ether amide)s derived from new diamine: 10,10-bis [4-(4-amino-2-pyridinoxy)phenyl]-9(10H)-anthracenone in 2020, Cited 22. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8.

A new aromatic diamine, 10,10-bis [4-(4-amino-2-pyridinoxy)phenyl]-9(10H)-anthracenone (BAPPA) was synthesized from anthrone as the starting material, and the corresponding pyridine- and anthrone-containing poly(ether amide)s (PEAs) were prepared from BAPPA with various aromatic diacid chlorides via a low-temperature solution polycondensation. The resulting PEAs having number-average molecular weights (M-n) of 29,500-33,400 g/mol with the polydispersity index ranged from 1.75 to 1.84, were all amorphous, and displayed excellent thermal stability with the glass transition temperatures of 263-355 degrees C, the temperatures of 415-441 degrees C at 5% weight loss and the higher than 50% residues at 800 degrees C in nitrogen. These new PEAs were soluble in polar solvents such as N-methyl-2-pyrrolidone, N,N-dimethylacetamide and pyridine, even almost in tetrahydrofuran at room temperature and could form transparent, strong and flexible films with tensile strengths of 84-97 MPa, tensile moduli of 2.1-3.2 GPa and elongations at break of 4-13%. Also, the present PEAs exhibited high optical transparence with the UV cutoff wavelength in the 342-362 nm range, and 83-90% transmittance at 500 nm. These results indicated the introduction of anthrone and pyridine groups into the backbone could improve the solubility and transparence of polyamides.

Formula: C14H10O. About Anthrone, If you have any questions, you can contact Zhou, YF; Huang, ZZ; Mao, XC; Song, C or concate me.

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem

An article Unraveling relation between nonlinear absorption and structure of push pull ornamented anthracenyl chalcone derivatives WOS:000569382500009 published article about 2-PHOTON ABSORPTION; OPTICAL PROPERTIES; MOLECULES; DESIGN; FLUORESCENCE; EXCITATION in [Saha, Amrita] Assam Univ, Dept Chem, Silchar 788011, India; [Singh, Asha; Chari, Rama; Jayabalan, J.] Raja Ramanna Ctr Adv Technol, Mat Sci Sect, Nano Sci Lab, Indore 452013, India; [Chari, Rama; Jayabalan, J.] Homi Bhabha Natl Inst, Training Sch Complex, Mumbai 400094, Maharashtra, India in 2020, Cited 50. HPLC of Formula: C14H10O. The Name is Anthrone. Through research, I have a further understanding and discovery of 90-44-8

Using green chemical method a series of fifteen systematically substituted 3-(9-substituted anthracen-10-yl)-1-(4-phenyl substituted)prop-2-en-1-one derivatives having high nonlinear absorption coefficient have been synthesized. The nonlinear absorption properties of these compounds were studied using nanosecond pulses at 532 nm wavelength. All 15 derivatives are found to show high nonlinear absorption in the range of 35-640 cm/GW. Among these the derivatives with-NO2 as one of the substitution group show higher nonlinear absorption. The origin of high nonlinear absorption with low linear absorption in the compounds has been attributed to two-step two-photon absorption process. We have shown that the energy bands of these compounds are distributed such that for excitation at 532 nm they have strong nonlinear absorption. These properties of the reported compounds make them a potential candidate for biological imaging and other applications which are based on nonlinear absorption. (C) 2020 Elsevier B.V. All rights reserved.

About Anthrone, If you have any questions, you can contact Saha, A; Singh, A; Chari, R; Jayabalan, J or concate me.. HPLC of Formula: C14H10O

Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem