Computed Properties of C7H8N2O. In 2019 EUR J ORG CHEM published article about ANTIFUNGAL ACTIVITY; MOLECULAR DOCKING; DERIVATIVES; CHEMISTRY; 3,4,4,5-TETRACHLORO-4H-1,2,6-THIADIAZINE; CYCLOPENTATHIADIAZINES; TETRACYANOETHYLENE; SUBSTITUTION; ACCESS; SPIRO in [Kalogirou, Andreas S.] European Univ Cyprus, Dept Life Sci, 6 Diogenis Str,POB 22006, CY-1516 Nicosia, Cyprus; [Kalogirou, Andreas S.; Kourtellaris, Andreas; Koutentis, Panayiotis A.] Univ Cyprus, Dept Chem, POB 20537, CY-1678 Nicosia, Cyprus in 2019, Cited 47. The Name is 2-Aminobenzamide. Through research, I have a further understanding and discovery of 88-68-6.
A three-step synthesis of 3 ‘,5 ‘-dichloro-1H-spiro(quinazo-line-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones starting from 3,4,4,5-tetra-chloro-4H-1,2,6-thiadiazine is presented. The latter reacts with 2-aminobenzonitriles to give 2-[(3,5-dichloro-4H-1,2,6-thiadiazin-4-ylid-ene)amino]benzonitriles, which affords, after hydration, the respective benzamides. Upon heating at reflux in EtOH or HFIP, the benzamides intramolecularly cyclize onto the thiadiazine C4 position to give 3 ‘,5 ‘-dichloro-1H-spiro(quinazoline-2,4 ‘-[1,2,6]thiadiazin)-4(3H)-ones. Single crystal X-ray crystallography supports the structure of two analogues. The chloride displacement of these new spiroquinazolinones was demonstrated by Stille coupling, and by reaction with methoxide to afford both the mono and bis-methoxy derivatives.
Computed Properties of C7H8N2O. Welcome to talk about 88-68-6, If you have any questions, you can contact Kalogirou, AS; Kourtellaris, A; Koutentis, PA or send Email.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem