The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Iodo-2-methylbutane( cas:616-14-8 ) is researched.SDS of cas: 616-14-8.Olah, George A.; Welch, John published the article 《Synthetic methods and reactions. XIII. Preparation of alkyl halides from alcohols with alkali halides in polyhydrogen fluoride/pyridine solution》 about this compound( cas:616-14-8 ) in Synthesis. Keywords: halide alkyl cycloalkyl adamantyl; benzyl halide; norbornyl halide. Let’s learn more about this compound (cas:616-14-8).
Thirty-nine RX (R = C4-8 alkyl, cyclopentyl, cyclohexyl, adamantyl, norbornyl, PhCH2; X = F, Cl, Br, I) were prepared by reaction of the corresponding ROH with MX (M = Na, K, NH4) in polyhydrogen fluoridepyridine. Thus, BuCH2OH was kept 1 hr with 70% HF-pyridine containing NaCl to give 89% BuCH2Cl.
The article 《Synthetic methods and reactions. XIII. Preparation of alkyl halides from alcohols with alkali halides in polyhydrogen fluoride/pyridine solution》 also mentions many details about this compound(616-14-8)SDS of cas: 616-14-8, you can pay attention to it, because details determine success or failure
Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem