Discovery of 616-14-8

When you point to this article, it is believed that you are also very interested in this compound(616-14-8)Application of 616-14-8 and due to space limitations, I can only present the most important information.

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 616-14-8, is researched, SMILESS is CCC(CI)C, Molecular C5H11IJournal, Article, Chemical Science called Metal-free C(sp3)-H functionalization of sulfonamides via strain-release rearrangement, Author is Hu, Jiefeng; Yang, Xianyu; Shi, Shasha; Cheng, Bo; Luo, Xiaoling; Lan, Yu; Loh, Teck-Peng, the main research direction is unsaturated imine preparation diastereoselective chemoselective DFT; fluorotosylamide tosylbenzaldimine carbon hydrogen functionalization strain release rearrangement.Application of 616-14-8.

A metal-free reaction system that enables C-H bond functionalization of aliphatic sulfonamides R(CH2)2N(F)Ts (R = decyl, cyclohexyl, oxan-4-yl, benzyl, etc.) using DABCO as a promoter under mild conditions, affording a series of α,β-unsaturated imines R1CH=C(R)CH=NTs (R1 = Ph, 4-chlorophenyl, 2,3-dihydro-1-benzofuran-5-yl, etc.) in good yields with high selectivities was presented. This protocol tolerates a broad range of functionalities and can serve as a powerful synthetic tool for the late-stage modification of complex compounds More importantly, control experiments and detailed DFT calculations suggest that this process involves [2 + 2] cyclization/ring-cleavage reorganization, which opens up a new platform for the establishment of other related reorganization reactions.

When you point to this article, it is believed that you are also very interested in this compound(616-14-8)Application of 616-14-8 and due to space limitations, I can only present the most important information.

Reference:
Thiomorpholine – Wikipedia,
Thiomorpholine | C4H9NS – PubChem