When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process. In an article, author is Dellinger, Douglas J., once mentioned the application of 86-48-6, Name is 1-Hydroxy-2-naphthoic acid, molecular formula is C11H8O3, molecular weight is 188.1794, MDL number is MFCD00003960, category is thiomorpholine. Now introduce a scientific discovery about this category, Synthetic Route of 86-48-6.
An improved method for the chemical synthesis of RNA was developed utilizing a streamlined method for the preparation of phosphoramidite monomers and a single-step deprotection of the resulting oligoribo-nucleotide product using 1,2-diamines under anhydrous conditions. The process is compatible with most standard heterobase protection and employs a 2′-O-(1,1-dioxo-1 lambda(6)-thiomorpholine-4-carbothioate) as a unique 2′-hydroxyl protective group. Using this approach, it was demonstrated that the chemical synthesis of RNA can be as simple and robust as the chemical synthesis of DNA.
Interested yet? This just the tip of the iceberg, If you are interested in 86-48-6, you can contact me at any time and look forward to more communication. Reference of 86-48-6.
Reference:
Thiomorpholine – Wikipedia,
,Thiomorpholine | C4H9NS – PubChem